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Drug Discovery and Evaluation: Methods in Clinical Pharmacology

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Cover of 'Drug Discovery and Evaluation: Methods in Clinical Pharmacology'

Table of Contents

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    Book Overview
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    Chapter 3 Dose Finding in Single Dose Studies by Allometric Scaling
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    Chapter 4 Pharmacokinetic Aspects of Multiple Dose Studies
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    Chapter 5 Dose Linearity and Proportionality
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    Chapter 6 Effects of Food Intake
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    Chapter 7 Special Populations: Profiling the Effect of Obesity on Drug Disposition and Pharmacodynamics
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    Chapter 8 Special Populations: Renal Impairment
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    Chapter 9 Special Populations: Influence of Hepatic Impairment
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    Chapter 10 Special Populations: Protein Binding Aspects
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    Chapter 11 The Human ADME Study
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    Chapter 12 Synthesis of Radiolabelled Compounds for Clinical Studies
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    Chapter 13 Drug–Drug Interaction Studies
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    Chapter 14 In Vitro/In Vivo Correlation for Drug-Drug Interactions
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    Chapter 15 Specific Studies for Formulation Development
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    Chapter 16 Absolute and Relative Bioavailability
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    Chapter 17 Bioequivalence
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    Chapter 18 Population Pharmacokinetics and Pharmacokinetic-Pharmacodynamics in Clinical Pharmacology
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    Chapter 20 In Silico Drug Repositioning Using Omics Data: The Potential and Pitfalls
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    Chapter 21 Toxicokinetics and Safety Ratios
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    Chapter 22 In/In Vivo Correlation for Transporters
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    Chapter 23 Relevance of Transporters in Clinical Studies
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    Chapter 24 Role of Clinical Pharmacokinetics Studies in Contemporary Oncology Drug Development
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    Chapter 25 Pharmacogenomics in and Its Influence on Pharmacokinetics
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    Chapter 26 PK/PD Approaches
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    Chapter 27 Methodologies of PD Assessment: Scales
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    Chapter 28 Methods in Clinical Pharmacology
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    Chapter 29 Pharmacodynamic Drug–Drug Interactions
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    Chapter 30 Methodologies of Safety Assessment in Clinical Pharmacology
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    Chapter 31 Pharmacodynamic Evaluation: Cardiovascular Methodologies
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    Chapter 32 Pharmacodynamic Evaluation: CNS Methodologies
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    Chapter 33 Pharmacodynamic Evaluation: Diabetic Methodologies
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    Chapter 34 Pharmacodynamic Evaluation: Inflammation/Immunology
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    Chapter 35 Pharmacodynamic Evaluation: Endocrinology
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    Chapter 36 Pharmacodynamic Evaluation: Dermatology
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    Chapter 37 Role of Clinical Pharmacodynamics Studies in the Era of Precision Medicines Against Cancer
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    Chapter 40 Chronopharmacology in Drug Development
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    Chapter 41 Clinical Aspects in Sleep Disorders and Apnea
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    Chapter 42 Clinical Quality Management System
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    Chapter 43 Clinical Studies in Geriatric Population
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    Chapter 44 Clinical Studies in Infants (Pediatric Pharmacology)
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    Chapter 45 Nanotechnology in Medicine
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    Chapter 46 Noninvasive Methodology (NMR)
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    Chapter 47 Personalized Medicine
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    Chapter 49 Pharmacodynamic Evaluation: Drug Dependency and Addiction
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    Chapter 50 Pharmacodynamic Evaluation: Gastroenterology
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    Chapter 51 Pharmacodynamic Evaluation: Gene Therapy
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    Chapter 52 Pharmacodynamic Evaluation: Herbal Medicine
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    Chapter 53 Pharmacodynamic Evaluation: Infectious Diseases
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    Chapter 54 Pharmacodynamic Evaluation: Ocular Pharmacology
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    Chapter 56 Pharmacodynamic Evaluation: Pain Methodologies
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    Chapter 58 Regulatory Guidance: ICH, EMA, FDA
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    Chapter 60 Traditional Chinese Medicine and Clinical Pharmacology
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    Chapter 61 Clinical Pharmacology of Tinnitus: Design and Evaluation
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    Chapter 62 Pharmacological Therapy in Inborn Errors of Metabolism
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    Chapter 63 General Principles of Pharmacovigilance in Clinical Development
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    Chapter 65 Characterization of Cardiac Electrophysiology Including ECG-Analysis
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    Chapter 67 Food Supplements: Definition and Classification
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    Chapter 68 Space Pharmacology: How Space Affects Pharmacology
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    Chapter 69 Gender Differences in Drug Therapy
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    Chapter 70 Medical Devices: Definition and Clinical Testing
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    Chapter 71 Future of Regulatory Safety Assessments
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    Chapter 72 Stem Cell Therapy
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Title
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Published by
Springer International Publishing, July 2020
DOI 10.1007/978-3-319-68864-0
ISBNs
978-3-31-968863-3, 978-3-31-968864-0
Editors

Hock, Franz J., Gralinski, Michael R.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 13%
Student > Bachelor 3 8%
Other 3 8%
Researcher 3 8%
Student > Ph. D. Student 3 8%
Other 6 15%
Unknown 16 41%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 9 23%
Biochemistry, Genetics and Molecular Biology 4 10%
Medicine and Dentistry 3 8%
Chemistry 2 5%
Agricultural and Biological Sciences 2 5%
Other 3 8%
Unknown 16 41%