Chapter title |
Molecular Typing of Coxiella burnetii (Q Fever).
|
---|---|
Chapter number | 19 |
Book title |
Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium
|
Published in |
Advances in experimental medicine and biology, June 2012
|
DOI | 10.1007/978-94-007-4315-1_19 |
Pubmed ID | |
Book ISBNs |
978-9-40-074314-4, 978-9-40-074315-1
|
Authors |
Massung RF, Cutler SJ, Frangoulidis D, Robert F. Massung, Sally J. Cutler, Dimitrios Frangoulidis, Massung, Robert F., Cutler, Sally J., Frangoulidis, Dimitrios |
Abstract |
Although we live in the age of genomics and the availability of complete genome sequences of Coxiella burnetii has increased our understanding of the genomic diversity of the agent, it is still somewhat a "query" microorganism. The epidemiology of Q fever is complex due to the worldwide distribution, reservoir and vector diversity, and a lack of studies defining the dynamic interaction between these factors. In addition Coxiella is an agent that could be used as a bioterror weapon. Therefore, typing methods that can discriminate strains and be used to trace back infections to their source are of paramount importance. In this chapter we provide an overview of historical and current typing methods and describe their advantages and limitations. Recently developed techniques such as MLVA and SNP typing have shown promise and improved the discrimination capacity and utility of genotyping methods for molecular epidemiologic studies of this challenging pathogen. |
X Demographics
Geographical breakdown
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Sweden | 1 | 4% |
Unknown | 26 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 33% |
Student > Ph. D. Student | 4 | 15% |
Student > Master | 3 | 11% |
Professor > Associate Professor | 2 | 7% |
Student > Doctoral Student | 2 | 7% |
Other | 2 | 7% |
Unknown | 5 | 19% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 9 | 33% |
Biochemistry, Genetics and Molecular Biology | 4 | 15% |
Veterinary Science and Veterinary Medicine | 4 | 15% |
Medicine and Dentistry | 4 | 15% |
Immunology and Microbiology | 1 | 4% |
Other | 0 | 0% |
Unknown | 5 | 19% |