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Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium

Overview of attention for book
Cover of 'Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 History and Prospects of Coxiella burnetii Research
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    Chapter 2 Phylogenetic Diversity, Virulence and Comparative Genomics
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    Chapter 3 Defense Mechanisms Against Oxidative Stress in Coxiella burnetii: Adaptation to a Unique Intracellular Niche
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    Chapter 4 Lipopolysaccharide of Coxiella burnetii
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    Chapter 5 Components of Protective Immunity
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    Chapter 6 Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium
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    Chapter 7 Coxiella Subversion of Intracellular Host Signaling
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    Chapter 8 The Coxiella burnetii Parasitophorous Vacuole.
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    Chapter 9 Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium
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    Chapter 10 Role of Lipids in Coxiella burnetii Infection
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    Chapter 11 Axenic Growth of Coxiella burnetii
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    Chapter 12 Developmental Biology of Coxiella burnetii
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    Chapter 13 Genetic Manipulation of Coxiella burnetii
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    Chapter 14 Role of Innate and Adaptive Immunity in the Control of Q Fever
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    Chapter 15 Immune Response and Coxiella burnetii Invasion
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    Chapter 16 Antigenic Analysis for Vaccines and Diagnostics
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    Chapter 17 Epidemic Q Fever in Humans in the Netherlands
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    Chapter 18 Coxiella-like Endosymbionts.
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    Chapter 19 Molecular Typing of Coxiella burnetii (Q Fever).
Attention for Chapter 8: The Coxiella burnetii Parasitophorous Vacuole.
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

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1 blog

Citations

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18 Dimensions

Readers on

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25 Mendeley
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Chapter title
The Coxiella burnetii Parasitophorous Vacuole.
Chapter number 8
Book title
Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium
Published in
Advances in experimental medicine and biology, June 2012
DOI 10.1007/978-94-007-4315-1_8
Pubmed ID
Book ISBNs
978-9-40-074314-4, 978-9-40-074315-1
Authors

Ghigo E, Colombo MI, Heinzen RA, Eric Ghigo, María I. Colombo, Robert A. Heinzen, Ghigo, Eric, Colombo, María I., Heinzen, Robert A.

Abstract

Coxiella burnetii is a bacterial intracellular parasite of eucaryotic cells that replicates within a membrane-bound compartment, or "parasitophorous vacuole" (PV). With the exception of human macrophages/monocytes, the consensus model of PV trafficking in host cells invokes endolysosomal maturation culminating in lysosome fusion. C. burnetii resists the degradative functions of the vacuole while at the same time exploiting the acidic pH for metabolic activation. While at first glance the mature PV resembles a large phagolysosome, an increasing body of evidence indicates the vacuole is in fact a specialized compartment that is actively modified by the pathogen. Adding to the complexity of PV biogenesis is new data showing vacuole engagement with autophagic and early secretory pathways. In this chapter, we review current knowledge of PV nature and development, and discuss disparate data related to the ultimate maturation state of PV harboring virulent or avirulent C. burnetii lipopolysaccharide phase variants in human mononuclear phagocytes.

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Unknown 24 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 20%
Researcher 4 16%
Student > Doctoral Student 3 12%
Student > Master 2 8%
Student > Bachelor 2 8%
Other 4 16%
Unknown 5 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 24%
Biochemistry, Genetics and Molecular Biology 6 24%
Veterinary Science and Veterinary Medicine 3 12%
Medicine and Dentistry 2 8%
Immunology and Microbiology 2 8%
Other 1 4%
Unknown 5 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2012.
All research outputs
#3,085,126
of 17,367,552 outputs
Outputs from Advances in experimental medicine and biology
#466
of 3,926 outputs
Outputs of similar age
#23,547
of 141,662 outputs
Outputs of similar age from Advances in experimental medicine and biology
#2
of 8 outputs
Altmetric has tracked 17,367,552 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,926 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 141,662 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.