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Alzheimer’s and Parkinson’s Diseases

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Cover of 'Alzheimer’s and Parkinson’s Diseases'

Table of Contents

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    Book Overview
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    Chapter 1 Visual Processing in Alzheimer’s Disease
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    Chapter 2 Stereopsis in Alzheimer’s Disease: Measuring Binocular Eye Movement
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    Chapter 3 Visual Cognition and Language Function in Alzheimer’s Disease
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    Chapter 4 Variables Affecting Visuospatial Primary Memory Defect in Alzheimer’s Disease: Preliminary Data
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    Chapter 5 Articulatory Deficits in Parkinson’s and Huntington’s Disease: An Acoustic Analysis
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    Chapter 6 Alzheimer’s Disease and Parkinson’s Disease with Dementia: Comparison of Cortical Blood Flow Demonstrated by Three-Dimensional Surface Display
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    Chapter 7 Correlation between Severity of Dementia and Decreased Cerebral Blood Flow in Alzheimer’s Disease and Senile Dementia of the Alzheimer’s Type
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    Chapter 8 Cerebral Blood Flow at Rest and During Cognitive Activation in Patients with Moderate Dementia of Alzheimer’s Type
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    Chapter 9 Usefulness of Monitoring Left Ventricular Function by an Ambulatory Radionuclide Detector (VEST) in Patients with Parkinson’s Disease and Postural Hypotension
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    Chapter 10 Frontal Dysfunction and Memory Deficit in Depression and Parkinson’s Disease
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    Chapter 11 Cellular Acetylcholine Receptor Expression in the Brain of Patients with Alzheimer’s and Parkinson’s Dementia
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    Chapter 12 The Contribution of Non-Dopaminergic Pathology to Cognitive, Motor and Affective Disability in Parkinson’s Disease
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    Chapter 13 Clinical, Pathological and Neurochemical Characteristics of Lewy Body Dementia
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    Chapter 14 Creutzfeldt-Jakob Disease (CJD) is Not an Infectious Disease
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    Chapter 15 Normal Production of the Amyloid β -Protein and the Pathogenesis of Alzheimer’s Disease
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    Chapter 16 Modulation of APP Processing by Neurotransmission
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    Chapter 17 Amyloid Precursor Protein (APP) Gene Expression is Controlled by a NFkB/Rel Related Protein
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    Chapter 18 Specific Cleavage of β -Amyloid Precursor Protein by an Integral Membrane Metalloendopeptidase
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    Chapter 19 Amyloidogenic Fragments of Amyloid Precursor Protein in Cells Cultured under Leupeptin
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    Chapter 20 A Leptomeningeal Protease Releasing the β Protein from the β Protein Precursor of Alzheimer’s Disease
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    Chapter 21 Cell Surface Receptor Mediated Control of Amyloid Precursor Protein Secretion: Involvement of Pleiotropic Signal Transduction Cascades
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    Chapter 22 Role of β -Amyloid in the Diagnosis of Neurodegenerative Diseases: Diffuse Lewy Body Disease Versus Alzheimer’s Disease
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    Chapter 23 Identification and Role of Non-Beta Components of Senile Plaque Amyloid in Alzheimer’s Disease
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    Chapter 24 β -Amyloid-Protein Immunoreactivity in Skin is Not a Reliable Marker of Alzheimer’s Disease: An Autopsy Controlled Study
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    Chapter 25 Metabolic and Functional Changes in βAPP Overexpressing Mouse Neuronal Cell Line: Muscarinic Receptor-Mediated Calcium Influx
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    Chapter 26 Effect of Ciliary Neurotrophic Factor on β -Amyloid Precursor Protein mRNA Expression
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    Chapter 27 Tau and High Molecular Weight Microtubule Associated Proteins in Aluminum-Induced Neurofibrillary Pathology
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    Chapter 28 Phenotypes and Genotypes of Apolipoprotein E in Japanese Patients with Late-Onset Sporadic Alzheimer’s Disease, Vascular Dementia, Down’s Syndrome or Parkinson’s Disease
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    Chapter 29 Risk Factors of Senile Dementias: Comparisons of Alzheimer’s Disease and Vascular Dementias
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    Chapter 30 Predictors of Institutional Care in Parkinson’s Disease
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    Chapter 31 Parkinson’s Disease: Biometrics Towards Nature-Nurture Puzzles
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    Chapter 32 Pathogenesis of Nigral Cell Death in Parkinson’s Disease
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    Chapter 33 Complement Components and GFAP Immunoreactivity within Alzheimer and Pathologic Aged Cortex
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    Chapter 34 Aluminum Neurotoxicity and Alzheimer’s Disease
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    Chapter 35 Distribution and Regulation of Interleukin 1- β Converting Enzyme in Rat and Man
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    Chapter 36 Localization and Density of Transferrin Binding Sites in the Nigrostriatal System of Control Subjects and Patients with Parkinson’s Disease
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    Chapter 37 Positron Emission Tomography (PET) Studies with Ligands for Cholinergic Receptors in the Human Brain
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    Chapter 38 Effect of Cholinergic Enhancers on Basal Forebrain Function Governing Cortical Cerebral Blood Flow
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    Chapter 39 Acetylcholinesterase is Not a Protease: Implications for Alzheimer’s Disease
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    Chapter 40 Does Tacrine Increase Acetylcholine Release from the Hippocampus?
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    Chapter 41 Aging-Induced Changes in the Autoregulation of Acetylcholine Release in the Rat Brain
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    Chapter 42 The Effect of Acetylcholinesterase Inhibitors on Acetylcholinesterase in Senile Plaque, Normal Human or Rat Brain, Human Erythrocyte or Rat Skeletal Muscle
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    Chapter 43 Quantity and Quality Changes of G Protein in Dementia of the Alzheimer Type
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    Chapter 44 Calcium Binding Proteins in the Septo-Hippocampal System of the Aged Rat
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    Chapter 45 Calcium Binding Proteins Differentiate Midbrain Dopaminergic Systems in Humans
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    Chapter 46 Enzymatic and Genetic Analysis of Cu/Zn Superoxide Dismutase in Non-Familial Alzheimer’s Disease
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    Chapter 47 Oxidative Stress and the Loss of Receptor Sensitivity in Aging
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    Chapter 48 Oxygen Toxicity Induces Apoptotic Neuronal Death in Cultured Rat Hippocampal Neurons
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    Chapter 49 Histochemical Demonstration of Monoamine Oxidase Activity in the Mouse Striatal Cholinergic Neurons and Marked Species Variations among Rodent Striata
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    Chapter 50 Cell Wall-Defective Forms of Nocardia Asteroides Require Tetrahydrobiopterin for Their Growth
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    Chapter 51 The Cholinotoxin AF64A Differentially Attenuates in Vitro Transcription of the Human Cholinesterase Genes
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    Chapter 52 Transient Alterations in the in Vivo Levels of Cholinesterase mRNAS Suggest Differential Adjustment to Cholinotoxic Stimuli
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    Chapter 53 Failure of the Neurotrophic ACTH(4–10) Analogue (BIM 22015) to Attenuate the AF64A-Induced Cholinergic Lesion in Rat Hippocampus
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    Chapter 54 Combined Nicotinic and Muscarinic Cholinergic and Serotonergic Blockade Selectively Impair Acquisition of Spatial Navigation
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    Chapter 55 Effect of JTP-2942, a Novel TRH Analogue, on Cognitive Function and Learning in Rodents
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    Chapter 56 Effects of a Novel TRH Analog, JTP-2942, on Cholinergic and Monoaminergic Neurons in the Brain
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    Chapter 57 Effect of Cortical Ischemic Damage on Primate Nucleus Basalis
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    Chapter 58 Intracerebroventricular Injection of Streptozotocin — An Animal Model for Sporadic Alzheimer’s Disease?
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    Chapter 59 Neuropathological Studies on Strains of Senescence Accelerated Mouse with Age Related Deficits in Learning and Memory
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    Chapter 60 Transgenic Rat and In-Vitro Studies of β-Amyloid Precursor Protein Processing
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    Chapter 61 “Kangenkaryu”, Chinese Herb Medicine, Improved Several Symptoms in Animal Models
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    Chapter 62 Catecholamine-Containing Biodegradable Microsphere Implants: An Overview of Experimental Studies in Dopamine-Lesioned Rats
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    Chapter 63 Alzheimer Disease: Major Neurotransmitter Deficits. Can they be Corrected?
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    Chapter 64 Recent Clinical Trials of Cholinomimetics for Patients with Alzheimer’s Disease in Japan
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    Chapter 65 New M1 Agonists: Selective Signaling, Neurotrophic-Like and Cognitive Effects — Implications in the Treatment of Alzheimer’s Disease
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    Chapter 66 Xanomeline: A Potent and Selective M1 Muscarinic Agonist in Vitro
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    Chapter 67 Absorption, Distribution, Metabolism, and Elimination of Radiolabeled Xanomeline in Healthy Male Subjects
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    Chapter 68 Single and Multiple Dose Safety, Pharmacodynamics and Pharmacokinetics of Xanomeline, a Novel Muscarinic M1 Agonist in Healthy Male Subjects
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    Chapter 69 Safety, Tolerance, and Pharmacokinetics of Xanomeline Tartrate: A Novel Muscarinic M1 Agonist in Healthy Elderly Subjects
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    Chapter 70 The Safety and Tolerance of Xanomeline Tartrate, an M1-Specific Cholinergic Agonist, in Patients with Alzheimer’s Disease
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    Chapter 71 CI-1002, a Novel Anticholinesterase and Muscarinic Antagonist
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    Chapter 72 Preclinical Evaluation of Linopirdine: Neurochemical and Behavioral Effects
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    Chapter 73 New Radioligands for PET-Examination of Central Muscarinic Receptors
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    Chapter 74 Gangliosides and Alzheimer’s Disease
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    Chapter 75 Estrogen in Clinical Trials for Dementia of Alzheimer Type
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    Chapter 76 MDL 72,974 A a Novel MAO-B Inhibitor: A European Multicentre Trial in Parkinson’s Disease as an Adjunct to Levodopa
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    Chapter 77 Neuronal Grafting in Parkinson’s Disease
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    Chapter 78 Environmentally-Derived Carbolinium Analogs of MPP + are Toxic to Dopaminergic Neurons in Vitro and in Vivo
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    Chapter 79 Presence of N-Methylated β -Carbolinium Ions and Potential Neurotoxic Analogs of MPP + in the Brain and Cerebrospinal Fluid of Parkinsonian and Non-Parkinsonian Patients
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    Chapter 80 Metabolic Bioactivation of Endogenous Isoquinolines as Dopaminergic Neurotoxins to Elicit Parkinson’s Disease
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    Chapter 81 Effect of Selegiline Administration on the Urinary Excretion of Dopamine-Derived Tetrahydroisoquinoline Alkaloids in Parkinson’s Disease Patients
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    Chapter 82 Inhibitory Effects of Endogenous Tetrahydroisoquinolines on Mitochondrial Respiration in Mouse Brain
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    Chapter 83 Dopamine-Derived Isoquinolines as Dopaminergic Neurotoxins and Oxidative Stress
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    Chapter 84 Effect of Chronic Administration of 1,2,3,4-Tetrahydroisoquinoline and Its Derivatives on the Monkey: Immunohistochemical Study
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    Chapter 85 The in Vitro Formation of 1,3-Dimethyl-1,2,3,4-Tetrahydroisoquinoline, a Neurotoxic Metabolite of Amphetamines
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    Chapter 86 A Novel Endogenous Amine, 1-Benzyl-1,2,3,4-Tetrahydroisoquinoline(1BnTIQ) in Parkinsonian CSF, and Its Toxicological Effect
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    Chapter 87 Neurotrophic Factor Therapy of Alzheimer’s Disease
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    Chapter 88 Potential Therapeutic Use of BDNF or NT-4/5 in Parkinson’s and Alzheimer’s Diseases
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    Chapter 89 Loss of Growth Inhibitory Factor in Degenerative Disease
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    Chapter 90 NGF Rescues Cholinergic Cell Bodies of the Primate Nucleus Basalis of Meynert and Induces Compensatory Synaptic Changes in Cortically-Lesioned Rats
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    Chapter 91 Microglia Secrete Plasminogen Which Enhances the Maturation of Mesencephalic Dopaminergic Neurons in Vitro
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    Chapter 92 Indicators of Oxidative Stress in Aged Fischer 344 Rats: Potential for Neurotrophic Treatment
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    Chapter 93 Regulation of Expression of the Low-Affinity NGF Receptor (p75LNGFR) Gene in Clonal Rat Pheochromocytoma PC12h-R Cells and Cultured Rat Basal Forebrain Cholinergic Neurons: Its Relation to Expression of the High-Affinity NGF Receptor ( trk A) Gene
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    Chapter 94 Molecular Biology of Catecholamine Systems: Multiple Tyrosine Hydroxylases in Different Simian Species, and in Humans in Relation to Parkinson’s Disease
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    Chapter 95 Population Diversity of Point Mutations in the Human AChE and BCHE Genes Predicts Variable Responses to Anticholinesterase Drugs
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    Chapter 96 Inhibition of Excitatory Amino Acid-Induced Neurotoxicity by a Tau Antisense Oligonucleotide in Primary Culture of Cerebellar Granule Cells
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    Chapter 97 Molecular Cloning of Human Growth Inhibitory Factor CDNA and Its Down-Regulation in Alzheimer’s Disease
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    Chapter 98 Expression of Human Tyrosine Hydroxylase-Chloramphenicol Acetyltransferase (CAT) Fusion Gene in the Brains of Transgenic Mice as Examined by CAT Immunocytochemistry
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    Chapter 99 Is the Point Mutation in Codon 331 of the Mitochondrial ND2 Gene Associated with Alzheimer’s Disease?
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    Chapter 100 A Novel Gene Delivery System for Neuroactive Peptides in Brain Tissue
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    Chapter 101 The Cholinergic Hypothesis of Geriatric Cognitive Dysfunction”: Consensus Meeting. January 24–25, 1993, Brescia, Italy
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Title
Alzheimer’s and Parkinson’s Diseases
Published by
Springer Science & Business Media, June 2013
DOI 10.1007/978-1-4757-9145-7
ISBNs
978-1-4757-9145-7, 978-1-4757-9147-1
Editors

Hanin, Israel, Yoshida, Mitsuo, Fisher, Abraham

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