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Proteins: membrane binding and pore formation. Introduction.

Overview of attention for book
Attention for Chapter 10: Hemolysin E (HlyE, ClyA, SheA) and related toxins.
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Chapter title
Hemolysin E (HlyE, ClyA, SheA) and related toxins.
Chapter number 10
Book title
Proteins Membrane Binding and Pore Formation
Published in
Advances in experimental medicine and biology, January 2010
DOI 10.1007/978-1-4419-6327-7_10
Pubmed ID
Book ISBNs
978-1-4419-6326-0, 978-1-4419-6327-7
Authors

Hunt S, Green J, Artymiuk PJ, Hunt, Stuart, Green, Jeffrey, Artymiuk, Peter J, Artymiuk, Peter J., Stuart Hunt, Jeffrey Green, Peter J. Artymiuk

Abstract

Certain strains of Escherichia coli, Salmonella enterica and Shigella flexneri produce a pore-forming toxin hemolysin E (HlyE), also known as cytolysin A (ClyA) and silent hemolysin, locus A (SheA). HlyE lyses erythrocytes and mammalian cells, forming transmembrane pores with a minimum internal diameter of-25 A. We review the current knowledge of HlyE structure and function in its solution and pore forms, models for membrane insertion, its potential use in biotechnology applications and its relationship to a wider superfamily of toxins.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Unknown 51 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 19%
Student > Master 9 17%
Student > Doctoral Student 8 15%
Researcher 6 11%
Student > Bachelor 5 9%
Other 4 8%
Unknown 11 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 16 30%
Agricultural and Biological Sciences 13 25%
Immunology and Microbiology 3 6%
Mathematics 2 4%
Chemistry 2 4%
Other 5 9%
Unknown 12 23%