| Chapter title |
Graphene Nanopore Devices for DNA Sensing
|
|---|---|
| Chapter number | 12 |
| Book title |
Nanopore-Based Technology
|
| Published in |
Methods in molecular biology, February 2012
|
| DOI | 10.1007/978-1-61779-773-6_12 |
| Pubmed ID | |
| Book ISBNs |
978-1-61779-772-9, 978-1-61779-773-6
|
| Authors |
Chris A. Merchant, Marija Drndić |
| Editors |
Maria E. Gracheva |
| Abstract |
We describe here a method for detecting the translocation of individual DNA molecules through nanopores created in graphene membranes. The devices consist of 1-5-nm thick graphene membranes with electron-beam sculpted nanopores from 5 to 10 nm in diameter. Due to the thin nature of the graphene membranes, and the reduced electrical resistance, we observe larger blocked currents than for traditional solid-state nanopores. We also show how ionic current noise levels can be reduced with the atomic-layer deposition of a few nanometers of titanium dioxide over the graphene surface. Unlike traditional solid-state nanopore materials that are insulating, graphene is an excellent electrical conductor, and its use opens the door to a new future class of nanopore devices in which electronic sensing and control is performed directly at the pore. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 8 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 50% |
| Professor | 1 | 13% |
| Student > Postgraduate | 1 | 13% |
| Student > Doctoral Student | 1 | 13% |
| Unknown | 1 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 2 | 25% |
| Engineering | 2 | 25% |
| Physics and Astronomy | 1 | 13% |
| Materials Science | 1 | 13% |
| Agricultural and Biological Sciences | 1 | 13% |
| Other | 0 | 0% |
| Unknown | 1 | 13% |