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X Demographics
Mendeley readers
Attention Score in Context
| Chapter title |
Adeno-Associated Virus as Gene Delivery Vehicle into the Retina.
|
|---|---|
| Chapter number | 7 |
| Book title |
Retinal Development
|
| Published in |
Methods in molecular biology, January 2020
|
| DOI | 10.1007/978-1-0716-0175-4_7 |
| Pubmed ID | |
| Book ISBNs |
978-1-07-160174-7, 978-1-07-160175-4
|
| Authors |
Deng, Shuyun, Oka, Kazuhiro, Shuyun Deng, Kazuhiro Oka |
| Abstract |
Initially discovered as a contaminant of adenovirus preparations, adeno-associated virus (AAV) has proved one of the most promising viral vectors for human gene therapy. The safety profile of AAV has been well-characterized in vivo studies, and the first gene therapy for patients with vision loss caused by Leber congenital amaurosis or retinitis pigmentosa was approved by the US Food and Drug Administration in 2017. This is an exciting era for investigators working on retina biology and treatments for blindness. In this chapter, we provide detailed methods for laboratory-scale production, purification, and characterization of AAV. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 12 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 25% |
| Unspecified | 2 | 17% |
| Student > Postgraduate | 2 | 17% |
| Student > Ph. D. Student | 1 | 8% |
| Unknown | 4 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 3 | 25% |
| Unspecified | 2 | 17% |
| Veterinary Science and Veterinary Medicine | 1 | 8% |
| Business, Management and Accounting | 1 | 8% |
| Unknown | 5 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2019.
All research outputs
#15,590,077
of 23,177,498 outputs
Outputs from Methods in molecular biology
#5,449
of 13,287 outputs
Outputs of similar age
#274,788
of 457,145 outputs
Outputs of similar age from Methods in molecular biology
#52
of 120 outputs
Altmetric has tracked 23,177,498 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,287 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 457,145 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 120 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.