Protein Allostery in Drug Discovery

Overview of attention for book

Protein Allostery in Drug Discovery

Springer Singapore

Table of Contents

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Book Overview
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Chapter 1 Allostery in Drug Development
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Chapter 2 Dynamic Protein Allosteric Regulation and Disease
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Chapter 3 Protein Allostery in Rational Drug Design
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Chapter 4 Progress in Allosteric Database
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Chapter 5 Correlation Between Allosteric and Orthosteric Sites
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Chapter 6 Characteristics of Allosteric Proteins, Sites, and Modulators
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Chapter 7 Advances in the Computational Identification of Allosteric Sites and Pathways in Proteins
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Chapter 8 Advances in NMR Methods to Identify Allosteric Sites and Allosteric Ligands
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Chapter 9 Interrogating Regulatory Mechanisms in Signaling Proteins by Allosteric Inhibitors and Activators: A Dynamic View Through the Lens of Residue Interaction Networks
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Chapter 10 GPCR Allosteric Modulator Discovery
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Chapter 11 Allosteric Small-Molecule Serine/Threonine Kinase Inhibitors
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Chapter 12 Allosteric Regulation of Protein Kinases Downstream of PI3-Kinase Signalling
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Chapter 13 Allosteric Modulators of Protein–Protein Interactions (PPIs)
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Chapter 14 Allosteric Modulation of Intrinsically Disordered Proteins
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Chapter 15 Engineering Allostery into Proteins

Attention for Chapter 11: Allosteric Small-Molecule Serine/Threonine Kinase Inhibitors

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Citations

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Identification of a potent PCNA‐p15‐interaction inhibitor by autodisplay‐based peptide library screening

Article in Microbial Biotechnology (April 2024)

Picornavirus 3C Proteins Intervene in Host Cell Processes through Proteolysis and Interactions with RNA

Article in Viruses (December 2023)

Targeting allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) to identify natural product inhibitors via structure-based computational approach

Article in Scientific Reports (October 2023)

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