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Heat Shock Protein 90 in Human Diseases and Disorders

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Cover of 'Heat Shock Protein 90 in Human Diseases and Disorders'

Table of Contents

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    Book Overview
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    Chapter 1 Regulatory Roles of HSP90-Rich Extracellular Vesicles
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    Chapter 2 HSP90-Based Heterocomplex as Essential Regulator for Cancer Disease
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    Chapter 3 Therapeutic Potential of Heat Shock Protein 90 Inhibitors in Colorectal Cancer
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    Chapter 4 Hsp90 in the Migration of Primordial Germ Cells: A Model to Study Long-Distance Cell Migration and Perhaps Cancer?
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    Chapter 5 Role of Heat Shock Protein 90 in Mammary Tumorigenesis
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    Chapter 6 Role of HSP90 Inhibitors in the Treatment of Cancer
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    Chapter 7 p53-Hsp90 Axis in Human Cancer
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    Chapter 8 HSP90 and Its Inhibitors for Cancer Therapy: Use of Nano-delivery System to Improve Its Clinical Application
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    Chapter 9 Hsp90 Is a Pivotal Player in Retinal Disease and Cancer
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    Chapter 10 Targeting Hsp-90 Related Disease Entities for Therapeutic Development
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    Chapter 11 HSP90: A Key Player in Metal-Induced Carcinogenesis?
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    Chapter 12 Hsp90 and Its Role in Heme-Maturation of Client Proteins: Implications for Human Diseases
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    Chapter 13 Moonlighting Functions of Heat Shock Protein 90
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    Chapter 14 Hsp90 as a Member of Dicarboxylate Clamp TPR Protein Interaction Network: Implication in Human Diseases and Prospect as a Drug Target
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    Chapter 15 The ‘Complex World’ of the Hsp90 Co-chaperone R2TP
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    Chapter 16 Functions of SGT1, a Co-chaperone
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    Chapter 17 Sti1/Hop Plays a Pivotal Role in Hsp90 Regulation Beyond Bridging Hsp70
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    Chapter 18 Hsp90: A Target for Susceptibilities and Substitutions in Biotechnological and Medicinal Application
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    Chapter 19 Screening Technique for Heat Shock Protein 90 Inhibitors from Natural Products
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    Chapter 20 Therapeutic Effects and Related Molecular Mechanisms of Celastrol, a Triterpenoid Natural Compound and Novel HSP90 Inhibitor Extracted from Plants of the Celastraceae Family
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    Chapter 21 Hsp90 Chaperone in Disease
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    Chapter 22 Theranostic Implications of Heat Shock Proteins in Idiopathic Pulmonary Fibrosis
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    Chapter 23 Heat Shock Protein 90 and Reproduction in Female Animals: Ovary, Oocyte and Early Embryo
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    Chapter 24 Heat Shock Protein 90 in Severe Trauma
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    Chapter 25 Hsp90: Is There an Unknown Role in Pain Neurobiology
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    Chapter 26 Heat Shock Protein 90 in Kidney Stone Disease
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    Chapter 27 HSP90 et al.: Chaperome and Proteostasis Deregulation in Human Disease
Attention for Chapter 6: Role of HSP90 Inhibitors in the Treatment of Cancer
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Chapter title
Role of HSP90 Inhibitors in the Treatment of Cancer
Chapter number 6
Book title
Heat Shock Protein 90 in Human Diseases and Disorders
Published by
Springer, Cham, January 2019
DOI 10.1007/978-3-030-23158-3_6
Book ISBNs
978-3-03-023157-6, 978-3-03-023158-3
Authors

Geraldine O’Sullivan Coyne, Cecilia Monge, Alice P. Chen, O’Sullivan Coyne, Geraldine, Monge, Cecilia, Chen, Alice P.

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