Chapter 1 Design Principles for Intestinal Permeability of Cyclic Peptides

Chapter 2 Strategies to Enhance Metabolic Stabilities

Chapter 3 Designing Cell-Permeable Macrocyclic Peptides

Chapter 4 Computational Methods for Studying Conformational Behaviors of Cyclic Peptides

Chapter 5 Computational Opportunities and Challenges in Finding Cyclic Peptide Modulators of Protein–Protein Interactions

Chapter 6 Design of Cyclic Peptides as Protein Recognition Motifs

Chapter 7 Design and Synthetic Strategies for Helical Peptides

Chapter 8 Click Chemistry for Cyclic Peptide Drug Design

Chapter 9 Frontier Between Cyclic Peptides and Macrocycles

Chapter 10 Building upon Nature’s Framework: Overview of Key Strategies Toward Increasing Drug-Like Properties of Natural Product Cyclopeptides and Macrocycles

Chapter 12 DNA-Encoded Macrocyclic Peptide Library

Chapter 13 Peptide Display Technologies

Chapter 14 Discovery of Functional Macrocyclic Peptides by Means of the RaPID System

Chapter 15 Genetic Selections with SICLOPPS Libraries: Toward the Identification of Novel Protein–Protein Interaction Inhibitors and Chemical Tools