Chapter title |
Camptothecin Production by In Vitro Cultures and Plant Regeneration in Ophiorrhiza Species
|
---|---|
Chapter number | 27 |
Book title |
Protocols for In Vitro Cultures and Secondary Metabolite Analysis of Aromatic and Medicinal Plants
|
Published in |
Methods in molecular biology, March 2009
|
DOI | 10.1007/978-1-60327-287-2_27 |
Pubmed ID | |
Book ISBNs |
978-1-60327-286-5, 978-1-60327-287-2
|
Authors |
Takashi Asano, Hiroshi Sudo, Mami Yamazaki, Kazuki Saito, Asano, Takashi, Sudo, Hiroshi, Yamazaki, Mami, Saito, Kazuki |
Editors |
S. Mohan Jain, Praveen K. Saxena |
Abstract |
Camptothecin derivatives are clinically used for the treatment of various human cancers. These derivatives are semi-synthesized from camptothecin which is isolated from the extracts of Camptotheca acuminata and Nothapodytes foetida. For the feasible production of camptothecin, the protocols for the tissue cultures of Ophiorrhiza species, O. pumila, O. liukiuensis and O. kuroiwai, have been established. The established aseptic plants and hairy roots produced camptothecin, and O. pumila hairy roots accumulated highest amount of camptothecin. Furthermore, we have established methods of plant regeneration from O. pumila hairy roots. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 2 | 12% |
Unknown | 15 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 4 | 24% |
Student > Ph. D. Student | 4 | 24% |
Unspecified | 1 | 6% |
Student > Bachelor | 1 | 6% |
Professor | 1 | 6% |
Other | 3 | 18% |
Unknown | 3 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 9 | 53% |
Unspecified | 1 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
Environmental Science | 1 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Other | 1 | 6% |
Unknown | 3 | 18% |