Targeted Drug Strategies for Cancer and Inflammation

Overview of attention for book

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Book Overview
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Chapter 1 Biological Role, Properties, and Therapeutic Applications of the Reduced Folate Carrier (RFC-SLC19A1) and the Proton-Coupled Folate Transporter (PCFT-SLC46A1)
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Chapter 2 Folate Receptors and Therapeutic Applications
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Chapter 3 Hormonal Control of Folate Receptor Genes
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Chapter 4 Folate Receptor-Targeted Radionuclide Imaging Agents
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Chapter 5 Folate Receptor Targeted Thymidylate Synthase Inhibitors
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Chapter 6 Discovery of Novel Antifolate Inhibitors of De Novo Purine Nucleotide Biosynthesis with Selectivity for High Affinity Folate Receptors and the Proton-Coupled Folate Transporter Over the Reduced Folate Carrier for Cellular Entry
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Chapter 7 Folate Receptor Targeted Cancer Chemotherapy
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Chapter 8 Anti-FR Antibody Generation and Engineering: Development of New Therapeutic Tools
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Chapter 9 Folate Receptor Positive Macrophages: Cellular Targets for Imaging and Therapy of Inflammatory and Autoimmune Diseases
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Chapter 10 Targeting Activated Macrophages Via a Functional Folate Receptor for Potential Treatment of Autoimmune/Inflammatory Disorders
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Chapter 11 Liposomes and Polymers in Folate-Targeted Cancer Therapeutics
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Chapter 12 Erratum to: Liposomes and Polymers in Folate-Targeted Cancer Therapeutics

Attention for Chapter 6: Discovery of Novel Antifolate Inhibitors of De Novo Purine Nucleotide Biosynthesis with Selectivity for High Affinity Folate Receptors and the Proton-Coupled Folate Transporter Over the Reduced Folate Carrier for Cellular Entry

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Citations

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Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors

Article in Bioorganic & Medicinal Chemistry (February 2021)

Translational considerations in nanomedicine: The oncology perspective

Article in Advanced Drug Delivery Reviews (June 2020)

Folate-graphene chelate manganese nanoparticles as a theranostic system for colon cancer MR imaging and drug delivery: In-vivo examinations

Article in Journal of Drug Delivery Science and Technology (December 2019)

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