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Clinical Trial Simulations

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Cover of 'Clinical Trial Simulations'

Table of Contents

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    Book Overview
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    Chapter 1 Clinical Trial Simulation and Quantitative Pharmacology
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    Chapter 2 Contribution of Modeling and Simulation Studies in the Regulatory Review: A European Regulatory Perspective
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    Chapter 3 Contribution of Modeling and Simulation in the Regulatory Review and Decision-Making: U.S. FDA Perspective
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    Chapter 4 Decision-Making in Drug Development: Application of a Model Based Framework for Assessing Trial Performance
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    Chapter 5 Decision-Making in Drug Development: Application of a Clinical Utility Index SM
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    Chapter 6 Adaptive Trial Designs
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    Chapter 7 Keys of Collaboration to Enhance Efficiency and Impact of Modeling and Simulation
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    Chapter 8 Leveraging Pharmacometrics in Early Phase Anti-inflamatory Drug Development
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    Chapter 9 The Application of Drug-Disease Models in the Development of Anti-Hyperglycemic Agents
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    Chapter 10 Modeling and Simulation in the Development of Cardiovascular Agents
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    Chapter 11 Viral Dynamic Modeling and Simulations in HIV and Hepatitis C
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    Chapter 12 A Model-Based PK/PD Antimicrobial Chemotherapy Drug Development Platform to Simultaneously Combat Infectious Diseases and Drug Resistance
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    Chapter 13 PKPD and Disease Modeling: Concepts and Applications to Oncology
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    Chapter 14 Application of Pharmacokinetic–Pharmacodynamic Modeling and Simulation for Erythropoietic Stimulating Agents
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    Chapter 15 Model Based Development of an Agent for the Treatment of Generalized Anxiety Disorder
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    Chapter 16 Balancing Efficacy and Safety in the Clinical Development of an Atypical Antipsychotic, Paliperidone Extended-Release
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    Chapter 17 Application of Modeling and Simulation in the Development of Protein Drugs
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    Chapter 18 Modeling and Simulation in Pediatric Research and Development
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    Chapter 19 Disease Progression Analysis: Towards Mechanism-Based Models
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    Chapter 20 Using a Systems Biology Approach to Explore Hypotheses Underlying Clinical Diversity of the Renin Angiotensin System and the Response to Antihypertensive Therapies
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    Chapter 21 Recent Developments in Physiologically Based Pharmacokinetic Modeling
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    Chapter 22 Covariate Distribution Models in Simulation
Overall attention for this book and its chapters
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Title
Clinical Trial Simulations
Published by
Springer-Verlag New York, January 2011
DOI 10.1007/978-1-4419-7415-0
ISBNs
978-1-4419-7414-3, 978-1-4419-7415-0, 978-1-4614-2784-1
Authors

Kimko, Hui C., Peck, Carl C.

Editors

Holly H. C. Kimko, Carl C. Peck

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Canada 1 2%
Unknown 40 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 14%
Researcher 5 12%
Other 3 7%
Student > Master 3 7%
Student > Doctoral Student 1 2%
Other 0 0%
Unknown 24 57%
Readers by discipline Count As %
Medicine and Dentistry 4 10%
Chemical Engineering 2 5%
Nursing and Health Professions 2 5%
Agricultural and Biological Sciences 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 5 12%
Unknown 25 60%