Development of Antibody-Based Therapeutics

Chapter 1 Translational Strategies for Development of Antibody-Based Therapeutics: An Overview

Chapter 2 Discovery Process for Antibody-Based Therapeutics

Chapter 3 Technologies for the Generation of Human Antibodies

Chapter 4 Application of Antibody Engineering in the Development of Next Generation Antibody-Based Therapeutics

Chapter 5 Biophysical Considerations for Development of Antibody-Based Therapeutics

Chapter 6 Considerations in Establishing Affinity Design Goals for Development of Antibody-Based Therapeutics

Chapter 7 Bioanalytical Considerations for Development of Antibody-Based Therapeutics: Pharmacokinetics and Immunogenicity

Chapter 8 Preclinical Considerations for Development of Antibody-Based Therapeutics in Oncology

Chapter 9 Factors Impacting the Tumor Localization and Distribution of Antibody-Based Therapeutics in Oncology

Chapter 10 Preclinical Safety Considerations for the Development of Antibody-Based Therapeutics

Chapter 11 Application of Pharmacokinetic/Pharmacodynamic Modeling in the Development of Antibody-Based Therapeutics

Chapter 12 Application of Population Pharmacokinetic-Pharmacodynamic Approaches in the Design of Translational Strategies for Development of Antibody-Based Therapeutics

Chapter 13 Translational Biomarkers: Essential Tools in Development of Antibody-Based Therapeutics

Chapter 14 Translational Research in Alzheimer’s Disease for Development of Antibody-Based Therapeutics

Chapter 15 Considerations in Manufacturing Process Development for Antibody-Based Therapeutics

Chapter 16 Strategies for Development of Next Generation Antibody-Based Therapeutics

Chapter 17 Immune Complex Therapies for Treatment of Immune Thrombocytopenia

Chapter 18 Application of Bioinformatics Principles for Target Evaluation

Chapter 19 Concluding Remarks