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p53 in the Clinics

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Cover of 'p53 in the Clinics'

Table of Contents

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    Book Overview
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    Chapter 1 TP53 : Coordinator of the Processes That Underlie the Hallmarks of Cancer
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    Chapter 2 The Inheritance of p53
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    Chapter 3 p53: Guardian of the Metabolome
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    Chapter 4 The p53 Family and Stem Cell Biology
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    Chapter 5 Mutant p53-Driven Tumorigenesis
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    Chapter 6 Humanised Mouse Models: Targeting the Murine p53 Locus with Human Sequences
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    Chapter 7 p53 Models for Mammary Carcinogenesis
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    Chapter 8 TP53 Somatic Mutations: Prognostic and Predictive Value in Human Cancers
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    Chapter 9 Assessing TP53 Status in Human Tumors: Lessons from Breast Cancer
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    Chapter 10 TP53 Germline Mutations: Genetics of Li–Fraumeni Syndrome
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    Chapter 11 Tp53 Gene Therapy for Cancer Treatment and Prevention
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    Chapter 12 Upstream Targets in the p53 Pathway
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    Chapter 13 p53-Reactivating Molecules as Research Tools and Anticancer Drugs
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    Chapter 14 Targeting Mutant p53 for Improved Cancer Therapy
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    Chapter 15 p53 Immunotherapy of Cancer
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    Chapter 16 Designing p53 Trials: A Surgical Oncologists View
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    Chapter 17 p53 in the Clinic: A Pathologist’s View
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    Chapter 18 Genetic Counseling for TP53 Germline Mutations
Attention for Chapter 8: TP53 Somatic Mutations: Prognostic and Predictive Value in Human Cancers
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