Attention for Chapter 6:
Beyond standard molecular dynamics: investigating the molecular mechanisms of g protein-coupled receptors with enhanced molecular dynamics methods.
Jennifer M Johnston, Marta Filizola, Jennifer M. Johnston, Johnston, Jennifer M., Filizola, Marta
Abstract
The majority of biological processes mediated by G Protein-Coupled Receptors (GPCRs) take place on timescales that are not conveniently accessible to standard molecular dynamics (MD) approaches, notwithstanding the current availability of specialized parallel computer architectures, and efficient simulation algorithms. Enhanced MD-based methods have started to assume an important role in the study of the rugged energy landscape of GPCRs by providing mechanistic details of complex receptor processes such as ligand recognition, activation, and oligomerization. We provide here an overview of these methods in their most recent application to the field.
Pharmacology, Toxicology and Pharmaceutical Science
1
13%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 October 2013.
All research outputs
#18,351,676
of 22,727,570 outputs
Outputs from Advances in experimental medicine and biology
#3,296
of 4,925 outputs
Outputs of similar age
#229,288
of 305,158 outputs
Outputs of similar age from Advances in experimental medicine and biology
#88
of 138 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,925 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
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We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
