| Chapter title |
Systems Medicine: The Future of Medical Genomics, Healthcare, and Wellness.
|
|---|---|
| Chapter number | 3 |
| Book title |
Systems Medicine
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3283-2_3 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3282-5, 978-1-4939-3283-2
|
| Authors |
Mansoor Saqi, Johann Pellet, Irina Roznovat, Alexander Mazein, Stéphane Ballereau, Bertrand De Meulder, Charles Auffray |
| Editors |
Ulf Schmitz, Olaf Wolkenhauer |
| Abstract |
Recent advances in genomics have led to the rapid and relatively inexpensive collection of patient molecular data including multiple types of omics data. The integration of these data with clinical measurements has the potential to impact on our understanding of the molecular basis of disease and on disease management. Systems medicine is an approach to understanding disease through an integration of large patient datasets. It offers the possibility for personalized strategies for healthcare through the development of a new taxonomy of disease. Advanced computing will be an important component in effectively implementing systems medicine. In this chapter we describe three computational challenges associated with systems medicine: disease subtype discovery using integrated datasets, obtaining a mechanistic understanding of disease, and the development of an informatics platform for the mining, analysis, and visualization of data emerging from translational medicine studies. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 41 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 24% |
| Student > Bachelor | 5 | 12% |
| Student > Ph. D. Student | 5 | 12% |
| Student > Doctoral Student | 3 | 7% |
| Other | 3 | 7% |
| Other | 9 | 21% |
| Unknown | 7 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 19% |
| Agricultural and Biological Sciences | 7 | 17% |
| Computer Science | 6 | 14% |
| Biochemistry, Genetics and Molecular Biology | 4 | 10% |
| Engineering | 2 | 5% |
| Other | 7 | 17% |
| Unknown | 8 | 19% |