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Assessing Rare Variation in Complex Traits

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Cover of 'Assessing Rare Variation in Complex Traits'

Table of Contents

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    Book Overview
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    Chapter 1 Calling Rare Variants from Genotype Data
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    Chapter 2 Calling Variants from Sequence Data
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    Chapter 3 Rare Variant Quality Control
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    Chapter 4 Rare Structural Variants
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    Chapter 5 Functional Annotation of Rare Genetic Variants
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    Chapter 6 The 1000 Genomes Project
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    Chapter 7 The UK10K Project: 10,000 UK Genome Sequences—Accessing the Role of Rare Genetic Variants in Health and Disease
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    Chapter 8 Population Isolates
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    Chapter 9 Natural Selection at Rare Variants
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    Chapter 10 Collapsing Approaches for the Association Analysis of Rare Variants
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    Chapter 11 Rare Variant Association Analysis: Beyond Collapsing Approaches
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    Chapter 12 Significance Thresholds for Rare Variant Signals
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    Chapter 13 Power of Rare Variant Aggregate Tests
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    Chapter 14 Replicating Sequencing-Based Association Studies of Rare Variants
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    Chapter 15 Meta-Analysis of Rare Variants
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    Chapter 16 Population Stratification of Rare Variants
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    Chapter 17 Use of Appropriate Controls in Rare-Variant Studies
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    Chapter 18 Trans-Ethnic Fine-Mapping of Rare Causal Variants
Attention for Chapter 6: The 1000 Genomes Project
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