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Predictive Biomarkers in Oncology

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Cover of 'Predictive Biomarkers in Oncology'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction to Predictive Biomarkers: Definitions and Characteristics
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    Chapter 2 Introduction to Clinical Trials, Clinical Trial Designs, and Statistical Terminology Used for Predictive Biomarker Research and Validation
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    Chapter 3 Overview of Methods Used in Predictive Biomarker Studies in a Molecular Anatomic Pathology Laboratory
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    Chapter 4 Significance of Immunohistochemistry and In Situ Hybridization Techniques for Predictive Biomarker Studies
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    Chapter 5 Overview of PCR-Based Technologies and Multiplexed Gene Analysis for Biomarker Studies
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    Chapter 6 Introduction to Microarray Technology
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    Chapter 7 Digital and Computational Pathology for Biomarker Discovery
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    Chapter 8 Detection of Predictive Biomarkers Using Liquid Biopsies
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    Chapter 9 Measurement of Predictive Cancer Biomarkers by Flow Cytometry
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    Chapter 10 Personalized Cancer Treatment and Patient Stratification Using Massive Parallel Sequencing (MPS) and Other OMICs Data
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    Chapter 11 Bioinformatic Methods and Resources for Biomarker Discovery, Validation, Development, and Integration
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    Chapter 12 Overview of Cell Signaling Pathways in Cancer
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    Chapter 13 Steroid Hormone and Nuclear Receptor Signaling Pathways
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    Chapter 14 Protein Kinase C Signaling in Carcinogenesis
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    Chapter 15 Roles of Rho/ROCK in Cancer Signaling
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    Chapter 16 Mitogen-Activated Protein Kinase (MAPK) Signaling
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    Chapter 17 Notch Signaling Pathway in Carcinogenesis
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    Chapter 18 Signaling of the ErbB Receptor Family in Carcinogenesis and the Development of Targeted Therapies
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    Chapter 19 Angiogenic Signaling Pathways and Anti-angiogenic Therapies in Human Cancer
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    Chapter 20 Role of PI3K/AKT/mTOR in Cancer Signaling
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    Chapter 21 Met Signaling in Carcinogenesis
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    Chapter 22 Role of Insulin-Like Growth Factor Receptors in Cancer Signaling
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    Chapter 23 Role of Wnt/β-Catenin Pathway in Cancer Signaling
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    Chapter 24 Hedgehog Signaling in Carcinogenesis
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    Chapter 25 TGF-β and the SMAD Signaling Pathway in Carcinogenesis
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    Chapter 26 Role of JAK-STAT Pathway in Cancer Signaling
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    Chapter 27 NF-κB Signaling Pathways in Carcinogenesis
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    Chapter 28 Immune Signaling in Carcinogenesis
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    Chapter 29 Predictive Biomarkers and Targeted Therapies in Immuno-oncology
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    Chapter 30 Role of Protein Tyrosine Phosphatases in Cancer Signaling
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    Chapter 31 Predictive and Prognostic Biomarkers in Myeloid Neoplasms
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    Chapter 32 Predictive Biomarkers and Targeted Therapies for Lymphoid Malignancies
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    Chapter 33 Targeted Therapies for Pediatric Central Nervous System Tumors
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    Chapter 34 Predictive Biomarkers and Targeted Therapies in Adult Brain Cancers
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    Chapter 35 Predictive Biomarkers and Targeted Therapies in Breast Cancer
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    Chapter 36 Predictive Biomarkers in Lung Cancer
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    Chapter 37 Predictive Biomarkers and Targeted Therapies in Genitourinary Cancers
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    Chapter 38 Predictive Biomarkers and Targeted Therapies in Colorectal Cancer
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    Chapter 39 Predictive Markers and Targeted Therapies in Gastroesophageal Cancer (GEC)
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    Chapter 40 Predictive Biomarkers and Targeted Therapies in Hepatic, Pancreatic, and Biliary Cancers
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    Chapter 41 Predictive Biomarkers and Targeted Therapies in Gynecological Cancers
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    Chapter 42 Predictive Biomarkers and Targeted Therapies in Head and Neck Cancer
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    Chapter 43 Predictive Biomarkers and Targeted Therapies in the Skin
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    Chapter 44 Predictive Biomarkers and Targeted Therapies in Sarcomas
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    Chapter 45 Predictive Markers and Targeted Therapies in Thyroid Cancer and Selected Endocrine Tumors
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    Chapter 46 The Response Evaluation Criteria in Solid Tumors (RECIST)
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    Chapter 47 IVDs and FDA Marketing Authorizations: A General Overview of FDA Approval Process of an IVD Companion Diagnostic Device in Oncology
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    Chapter 48 Quality Control of Immunohistochemical and In Situ Hybridization Predictive Biomarkers for Patient Treatment: Experience from International Guidelines and International Quality Control Schemes
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    Chapter 49 Use of Companion Diagnostics (CDx) and Predictive Biomarkers for Cancer Targeted Therapy: Clinical Applications in Precision Medicine
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    Chapter 50 Policy Issues in the Clinical Development and Use of Predictive Biomarkers for Molecular Targeted Therapies
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    Chapter 51 Role of Central Laboratories in Research, Validation, and Application of Predictive Biomarkers
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    Chapter 52 Prominent Precision Medicine Clinical Trials in Oncology Around the World
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    Chapter 53 Precision Medicine Clinical Trials: Successes and Disappointments, Challenges and Opportunities – Lessons Learnt
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    Chapter 54 FDA-Approved Targeted Therapies in Oncology
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Title
Predictive Biomarkers in Oncology
Published by
Springer International Publishing, November 2018
DOI 10.1007/978-3-319-95228-4
ISBNs
978-3-31-995227-7, 978-3-31-995228-4
Editors

Badve, Sunil, Kumar, George Louis

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 117 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 6%
Student > Bachelor 6 5%
Student > Master 3 3%
Researcher 2 2%
Unspecified 1 <1%
Other 0 0%
Unknown 98 84%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 4%
Chemistry 3 3%
Agricultural and Biological Sciences 3 3%
Nursing and Health Professions 2 2%
Unspecified 1 <1%
Other 3 3%
Unknown 100 85%