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Chromosomal Instability in Cancer Cells

Overview of attention for book
Cover of 'Chromosomal Instability in Cancer Cells'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 DNA Repair and Chromosomal Translocations
  3. Altmetric Badge
    Chapter 2 CINcere Modelling: What Have Mouse Models for Chromosome Instability Taught Us?
  4. Altmetric Badge
    Chapter 3 Telomere Dysfunction, Chromosomal Instability and Cancer
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    Chapter 4 Genetic Instability and Disease Prognostication.
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    Chapter 5 Causes of Chromosomal Instability.
  7. Altmetric Badge
    Chapter 6 Patterns of Chromosomal Aberrations in Solid Tumors.
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    Chapter 7 Yeast as Models of Mitotic Fidelity.
  9. Altmetric Badge
    Chapter 8 The Diverse Effects of Complex Chromosome Rearrangements and Chromothripsis in Cancer Development
  10. Altmetric Badge
    Chapter 9 Consequences of Aneuploidy in Cancer: Transcriptome and Beyond.
Attention for Chapter 9: Consequences of Aneuploidy in Cancer: Transcriptome and Beyond.
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  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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1 X user

Citations

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4 Dimensions

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Chapter title
Consequences of Aneuploidy in Cancer: Transcriptome and Beyond.
Chapter number 9
Book title
Chromosomal Instability in Cancer Cells
Published in
Recent results in cancer research Fortschritte der Krebsforschung Progrès dans les recherches sur le cancer, January 2015
DOI 10.1007/978-3-319-20291-4_9
Pubmed ID
26376878
Book ISBNs
978-3-31-920290-7, 978-3-31-920291-4
Authors

Dürrbaum, Milena, Storchová, Zuzana, Milena Dürrbaum, Zuzana Storchová

Abstract

Cancer cells differ from normal healthy cells in multiple aspects ranging from altered cellular signaling through metabolic changes to aberrant chromosome content, so called aneuploidy. The large-scale changes in copy numbers of chromosomes or large chromosomal regions due to aneuploidy alter significantly the gene expression, as several hundreds of genes are gained or lost. Comparison of quantitative genome, transcriptome and proteome data enables dissection of the molecular causes that underlie the gene expression changes observed in cancer cells and provides a new perspective on the molecular consequences of aneuploidy. Here, we will map to what degree aneuploidy affects the expression of genes located on the affected chromosomes. We will also address the effects of aneuploidy on global gene expression in cancer cells as well as whether and how it may contribute to the physiology of cancer cells.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 27%
Researcher 3 20%
Student > Bachelor 2 13%
Student > Master 2 13%
Professor 1 7%
Other 2 13%
Unknown 1 7%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 53%
Agricultural and Biological Sciences 3 20%
Medicine and Dentistry 2 13%
Unknown 2 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2016.
All research outputs
#18,434,182
of 22,837,982 outputs
Outputs from Recent results in cancer research Fortschritte der Krebsforschung Progrès dans les recherches sur le cancer
#119
of 171 outputs
Outputs of similar age
#255,943
of 353,212 outputs
Outputs of similar age from Recent results in cancer research Fortschritte der Krebsforschung Progrès dans les recherches sur le cancer
#5
of 9 outputs
Altmetric has tracked 22,837,982 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 171 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,212 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.

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