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Endocytosis and Signaling

Overview of attention for book
Cover of 'Endocytosis and Signaling'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 The Endosomal Network: Mediators and Regulators of Endosome Maturation
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    Chapter 2 Integration of the Endocytic System into the Network of Cellular Functions
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    Chapter 3 GTPases Rac1 and Ras Signaling from Endosomes
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    Chapter 4 ESCRT and Membrane Protein Ubiquitination
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    Chapter 5 Retromer and Its Role in Regulating Signaling at Endosomes
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    Chapter 6 The Lysosome and Intracellular Signalling
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    Chapter 7 Interplay of Endocytosis and Growth Factor Receptor Signalling
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    Chapter 8 Role of the Endocytosis of Caveolae in Intracellular Signaling and Metabolism
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    Chapter 9 EGFR Trafficking in Physiology and Cancer
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    Chapter 10 Evolving View of Membrane Trafficking and Signaling Systems for G Protein-Coupled Receptors
  12. Altmetric Badge
    Chapter 11 Endosomal Trafficking During Mitosis and Notch-Dependent Asymmetric Division
Attention for Chapter 5: Retromer and Its Role in Regulating Signaling at Endosomes
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Citations

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Chapter title
Retromer and Its Role in Regulating Signaling at Endosomes
Chapter number 5
Book title
Endocytosis and Signaling
Published in
Progress in molecular and subcellular biology, August 2018
DOI 10.1007/978-3-319-96704-2_5
Pubmed ID
30097774
Book ISBNs
978-3-31-996703-5, 978-3-31-996704-2
Authors

Matthew N. J. Seaman, Seaman, Matthew N. J.

Abstract

The retromer complex is a key element of the endosomal protein sorting machinery being involved in trafficking of proteins from endosomes to the Golgi and also endosomes to the cell surface. There is now accumulating evidence that retromer also has a prominent role in regulating the activity of many diverse signaling proteins that traffic through endosomes and this activity has profound implications for the functioning of many different cell and tissue types from neuronal cells to cells of the immune system to specialized polarized epithelial cells of the retina. In this review, the protein composition of the retromer complex will be described along with many of the accessory factors that facilitate retromer-mediated endosomal protein sorting to detail how retromer activity contributes to the regulation of several distinct signaling pathways.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 33%
Other 3 13%
Researcher 3 13%
Professor 2 8%
Student > Master 2 8%
Other 2 8%
Unknown 4 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 29%
Neuroscience 6 25%
Medicine and Dentistry 2 8%
Immunology and Microbiology 1 4%
Business, Management and Accounting 1 4%
Other 2 8%
Unknown 5 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2018.
All research outputs
#20,529,980
of 23,099,576 outputs
Outputs from Progress in molecular and subcellular biology
#64
of 82 outputs
Outputs of similar age
#289,371
of 331,523 outputs
Outputs of similar age from Progress in molecular and subcellular biology
#4
of 6 outputs
Altmetric has tracked 23,099,576 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 82 research outputs from this source. They receive a mean Attention Score of 2.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,523 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.

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