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Myelin

Overview of attention for book
Cover of 'Myelin'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Electron Microscopy for the Analysis of Peripheral Nerve Myelin
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    Chapter 2 Immunohistochemical Analysis of Myelin Structures
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    Chapter 3 Visualization and Time-Lapse Microscopy of Myelinating Glia In Vivo in Zebrafish
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    Chapter 4 Lipidomics Profiling of Myelin
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    Chapter 5 Mapping Lipid Distribution in Rat Sciatic Nerve Using Imaging Mass Spectrometry
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    Chapter 6 Proteomics Analysis of Myelin Composition
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    Chapter 7 Isolation and Purification of Primary Rodent Schwann Cells
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    Chapter 8 Isolation, Expansion, and Maturation of Oligodendrocyte Lineage Cells Obtained from Rat Neonatal Brain and Optic Nerve
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    Chapter 9 DRG Neuron/Schwann Cells Myelinating Cocultures
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    Chapter 10 Neuron/Oligodendrocyte Myelination Coculture
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    Chapter 11 Organotypic Slice Cultures to Study Oligodendrocyte Proliferation, Fate, and Myelination
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    Chapter 12 Modeling PNS and CNS Myelination Using Microfluidic Chambers
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    Chapter 13 Modeling CNS Myelination Using Micropillar Arrays
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    Chapter 14 A Central Nervous System Axonal Myelination Assay for High-Throughput Screening
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    Chapter 15 Analyzing Autophagic Flux in Nerve Cultures
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    Chapter 16 Subcellular Optogenetic Stimulation Platform for Studying Activity-Dependent Axon Myelination In Vitro
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    Chapter 17 Active Induction of Experimental Autoimmune Encephalomyelitis (EAE) with MOG35–55 in the Mouse
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    Chapter 18 Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin
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    Chapter 19 Myelin Protein Zero 180–199 Peptide Induced Experimental Autoimmune Neuritis in C57BL/6 Mice
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    Chapter 20 Transection and Crush Models of Nerve Injury to Measure Repair and Remyelination in Peripheral Nerve
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    Chapter 21 In Vivo Introduction of Transgenes into Mouse Sciatic Nerve Cells Using Viral Vectors
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    Chapter 22 Intrathecal Delivery of Viral Vectors for Gene Therapy
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    Chapter 23 Efficient Gene Transfer to Myelinating Schwann Cells in the Rodent Sciatic Nerve Using In Vivo Electroporation
Attention for Chapter 18: Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin
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Chapter title
Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin
Chapter number 18
Book title
Myelin
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7862-5_18
Pubmed ID
30006714
Book ISBNs
978-1-4939-7861-8, 978-1-4939-7862-5
Authors

Chenyi Wang, Mark R. Kotter, Wang, Chenyi, Kotter, Mark R.

Abstract

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease in the central nervous system (CNS) characterized by loss of oligodendrocytes, myelin axons, and neurons. Remyelination is an endogenous repair mechanism, which recovers the loss of myelin and is able to preserve functional axons. The hope is that the development of new treatments aiming at promoting remyelination will halt and potentially partially reverse the progressive neurological decline in MS. The development of such drugs requires adequate models. In this chapter, we will discuss the surgical procedure of injection of lysolecithin into ventral thoraco-lumbar spinal cord white matter of mice, which is particularly suitable for investigating remyelination using transgenic animals.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 35%
Student > Master 4 11%
Student > Bachelor 3 8%
Other 2 5%
Researcher 2 5%
Other 5 14%
Unknown 8 22%
Readers by discipline Count As %
Neuroscience 11 30%
Biochemistry, Genetics and Molecular Biology 6 16%
Medicine and Dentistry 3 8%
Agricultural and Biological Sciences 2 5%
Immunology and Microbiology 2 5%
Other 4 11%
Unknown 9 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2019.
All research outputs
#15,540,879
of 23,096,849 outputs
Outputs from Methods in molecular biology
#5,412
of 13,208 outputs
Outputs of similar age
#270,149
of 442,670 outputs
Outputs of similar age from Methods in molecular biology
#596
of 1,499 outputs
Altmetric has tracked 23,096,849 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,208 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,670 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,499 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.

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