Chapter title |
Cardiomyocyte Differentiation from Human Embryonic Stem Cells
|
---|---|
Chapter number | 5 |
Book title |
Experimental Models of Cardiovascular Diseases
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-8597-5_5 |
Pubmed ID | |
Book ISBNs |
978-1-4939-8596-8, 978-1-4939-8597-5
|
Authors |
Silvia Mazzotta, Adam T. Lynch, Stefan Hoppler, Mazzotta, Silvia, Lynch, Adam T., Hoppler, Stefan |
Abstract |
In vitro generated human cardiomyocytes hold the ultimate promise for heart patients for repair of injured or diseased myocardium, but they also provide experimental models for studying normal cardiomyocyte development, for disease modeling and for drug development. Here we provide reliable protocols for differentiation of human embryonic stem cells into functional cardiomyocytes, together with Notes about troubleshooting and optimizing such protocols for specific cell lines. This chapter also briefly discusses other published protocols and those further adapted for differentiation of induced pluripotent stem cells into cardiomyocytes. |
X Demographics
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United Kingdom | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 12 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 4 | 33% |
Student > Bachelor | 3 | 25% |
Student > Postgraduate | 1 | 8% |
Unknown | 4 | 33% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 5 | 42% |
Business, Management and Accounting | 1 | 8% |
Agricultural and Biological Sciences | 1 | 8% |
Medicine and Dentistry | 1 | 8% |
Unknown | 4 | 33% |