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Experimental Models of Cardiovascular Diseases

Overview of attention for book
Cover of 'Experimental Models of Cardiovascular Diseases'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Experimental Models of Cardiovascular Diseases: Overview
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    Chapter 2 An Introduction to Computational Modeling of Cardiac Electrophysiology and Arrhythmogenicity
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    Chapter 3 Isolation of Atrial and Ventricular Cardiomyocytes for In Vitro Studies
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    Chapter 4 Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells
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    Chapter 5 Cardiomyocyte Differentiation from Human Embryonic Stem Cells
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    Chapter 6 Induction of Human Induced Pluripotent Stem Cells to Cardiomyocytes Using Embryoid Bodies
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    Chapter 7 Measuring Cardiomyocyte Contractility and Calcium Handling In Vitro
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    Chapter 8 Langendorff Perfusion Method as an Ex Vivo Model to Evaluate Heart Function in Rats
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    Chapter 9 Methods for the Preparation of an Excised, Cross-Circulated Rat Heart
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    Chapter 10 Optical Action Potential Mapping in Acute Models of Ischemia–Reperfusion Injury: Probing the Arrhythmogenic Role of the Mitochondrial Translocator Protein
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    Chapter 11 Cardiac Tissue Engineering Models of Inherited and Acquired Cardiomyopathies
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    Chapter 12 Badimon Perfusion Chamber: An Ex Vivo Model of Thrombosis
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    Chapter 13 Ischemic Model of Heart Failure in Rats and Mice
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    Chapter 14 Conventional Method of Transverse Aortic Constriction in Mice
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    Chapter 15 Characterization of the Differential Progression of Left Ventricular Remodeling in a Rat Model of Pressure Overload Induced Heart Failure. Does Clip Size Matter?
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    Chapter 16 Isoproterenol-Induced Heart Failure Mouse Model Using Osmotic Pump Implantation
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    Chapter 17 Rat Model of Cardiotoxic Drug-Induced Cardiomyopathy
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    Chapter 18 Pulmonary Artery Hypertension Model in Rats by Monocrotaline Administration
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    Chapter 19 The Sugen 5416/Hypoxia Mouse Model of Pulmonary Arterial Hypertension
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    Chapter 20 Mouse Model of Wire Injury-Induced Vascular Remodeling
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    Chapter 21 The Mouse Aortocaval Fistula Model with Intraluminal Drug Delivery
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    Chapter 22 A Pig Model of Myocardial Infarction: Catheter-Based Approaches
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    Chapter 23 Ovine Model of Ischemic Mitral Regurgitation
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    Chapter 24 Canine Model of Pacing-Induced Heart Failure
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    Chapter 25 Swine Model of Mitral Regurgitation Induced Heart Failure
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    Chapter 26 Pig Model of Increased Cardiac Afterload Induced by Ascending Aortic Banding
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    Chapter 27 Large Porcine Model of Profound Acute Ischemic Cardiogenic Shock
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    Chapter 28 Chronic Pulmonary Artery Embolization Models in Large Animals
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    Chapter 29 Modeling Pulmonary Hypertension: A Pig Model of Postcapillary Pulmonary Hypertension
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    Chapter 30 Development and Multiparametric Evaluation of Experimental Atherosclerosis in Rabbits
Attention for Chapter 5: Cardiomyocyte Differentiation from Human Embryonic Stem Cells
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

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Chapter title
Cardiomyocyte Differentiation from Human Embryonic Stem Cells
Chapter number 5
Book title
Experimental Models of Cardiovascular Diseases
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-8597-5_5
Pubmed ID
Book ISBNs
978-1-4939-8596-8, 978-1-4939-8597-5
Authors

Silvia Mazzotta, Adam T. Lynch, Stefan Hoppler, Mazzotta, Silvia, Lynch, Adam T., Hoppler, Stefan

Abstract

In vitro generated human cardiomyocytes hold the ultimate promise for heart patients for repair of injured or diseased myocardium, but they also provide experimental models for studying normal cardiomyocyte development, for disease modeling and for drug development. Here we provide reliable protocols for differentiation of human embryonic stem cells into functional cardiomyocytes, together with Notes about troubleshooting and optimizing such protocols for specific cell lines. This chapter also briefly discusses other published protocols and those further adapted for differentiation of induced pluripotent stem cells into cardiomyocytes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 33%
Student > Bachelor 3 25%
Student > Postgraduate 1 8%
Unknown 4 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 42%
Business, Management and Accounting 1 8%
Agricultural and Biological Sciences 1 8%
Medicine and Dentistry 1 8%
Unknown 4 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2018.
All research outputs
#13,104,474
of 23,094,276 outputs
Outputs from Methods in molecular biology
#3,331
of 13,208 outputs
Outputs of similar age
#207,578
of 442,658 outputs
Outputs of similar age from Methods in molecular biology
#283
of 1,499 outputs
Altmetric has tracked 23,094,276 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,208 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,658 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 1,499 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.