Chapter title |
Osteochondral Angiogenesis and Promoted Vascularization: New Therapeutic Target
|
---|---|
Chapter number | 14 |
Book title |
Osteochondral Tissue Engineering
|
Published in |
Advances in experimental medicine and biology, January 2018
|
DOI | 10.1007/978-3-319-76735-2_14 |
Pubmed ID | |
Book ISBNs |
978-3-31-976734-5, 978-3-31-976735-2
|
Authors |
Luis García-Fernández, García-Fernández, Luis |
Abstract |
The control of the different angiogenic process is an important point in osteochondral regeneration. Angiogenesis is a prerequisite for osteogenesis in vivo; insufficient neovascularization of bone constructs after scaffold implantation resulted in hypoxia and cellular necrosis. Otherwise, angiogenesis must be avoided in chondrogenesis; vascularization of the cartilage contributes to structural damage and pain. Finding a balance between these processes is important to design a successful treatment for osteochondral regeneration. This chapter shows the most important advances in the control of angiogenic process for the treatment of osteochondral diseases focused on the administration of pro- or anti-angiogenic factor and the design of the scaffold. |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 10 | 100% |
Demographic breakdown
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Student > Bachelor | 3 | 30% |
Researcher | 2 | 20% |
Librarian | 1 | 10% |
Unspecified | 1 | 10% |
Student > Master | 1 | 10% |
Other | 1 | 10% |
Unknown | 1 | 10% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 2 | 20% |
Biochemistry, Genetics and Molecular Biology | 2 | 20% |
Veterinary Science and Veterinary Medicine | 1 | 10% |
Arts and Humanities | 1 | 10% |
Unspecified | 1 | 10% |
Other | 2 | 20% |
Unknown | 1 | 10% |