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HLA Typing

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Cover of 'HLA Typing'

Table of Contents

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    Book Overview
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    Chapter 1 The Past, Present, and Future of HLA Typing in Transplantation
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    Chapter 2 Role of Human Leukocyte Antigens (HLA) in Autoimmune Diseases
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    Chapter 3 The IPD Databases: Cataloguing and Understanding Allele Variants
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    Chapter 4 Allele Frequency Net Database
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    Chapter 5 High-Resolution HLA-Typing by Next-Generation Sequencing of Randomly Fragmented Target DNA
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    Chapter 6 High-Throughput Contiguous Full-Length Next-Generation Sequencing of HLA Class I and II Genes from 96 Donors in a Single MiSeq Run
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    Chapter 7 Application of High-Throughput Next-Generation Sequencing for HLA Typing on Buccal Extracted DNA
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    Chapter 8 Super High Resolution for Single Molecule-Sequence-Based Typing of Classical HLA Loci Using Ion Torrent PGM
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    Chapter 9 High-Resolution Full-Length HLA Typing Method Using Third Generation (Pac-Bio SMRT) Sequencing Technology
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    Chapter 10 Full-Length HLA Class I Genotyping with the MinION Nanopore Sequencer
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    Chapter 11 Imputation-Based HLA Typing with SNPs in GWAS Studies
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    Chapter 12 In Silico Typing of Classical and Non-classical HLA Alleles from Standard RNA-Seq Reads
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    Chapter 13 PHLAT: Inference of High-Resolution HLA Types from RNA and Whole Exome Sequencing
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    Chapter 14 Using Exome and Amplicon-Based Sequencing Data for High-Resolution HLA Typing with ATHLATES
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    Chapter 15 HLA Typing from Short-Read Sequencing Data with OptiType
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    Chapter 16 Comprehensive HLA Typing from a Current Allele Database Using Next-Generation Sequencing Data
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    Chapter 17 Accurate Assembly and Typing of HLA using a Graph-Guided Assembler Kourami
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    Chapter 18 AmpliSAS and AmpliHLA: Web Server Tools for MHC Typing of Non-Model Species and Human Using NGS Data
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    Chapter 19 HLA Haplotype Frequency Estimation from Real-Life Data with the Hapl-o-Mat Software
Attention for Chapter 15: HLA Typing from Short-Read Sequencing Data with OptiType
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Chapter title
HLA Typing from Short-Read Sequencing Data with OptiType
Chapter number 15
Book title
HLA Typing
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-8546-3_15
Pubmed ID
Book ISBNs
978-1-4939-8545-6, 978-1-4939-8546-3
Authors

András Szolek, Szolek, András

Abstract

The established standards for HLA genotyping rely on targeted DNA sequencing techniques. However, the increasing abundance of short-read sequencing data has prompted a demand for computational tools capable of HLA typing from general purpose sequencing data as well. OptiType is a software that performs HLA typing from short-read DNA and RNA sequencing data, and this chapter guides the user through its installation and usage.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Other 3 23%
Researcher 2 15%
Student > Master 2 15%
Student > Bachelor 1 8%
Lecturer 1 8%
Other 1 8%
Unknown 3 23%
Readers by discipline Count As %
Computer Science 2 15%
Medicine and Dentistry 2 15%
Agricultural and Biological Sciences 1 8%
Arts and Humanities 1 8%
Immunology and Microbiology 1 8%
Other 1 8%
Unknown 5 38%