Report for: Interplay between Metal Ions and Nucleic Acids

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Chapter title	Metal-Mediated Base Pairs in Nucleic Acids with Purine- and Pyrimidine-Derived Nucleosides
Chapter number	11
Book title	Interplay between Metal Ions and Nucleic Acids
Published in	Metal ions in life sciences, February 2016
DOI	10.1007/978-94-007-2172-2_11
Pubmed ID	22210344
Book ISBNs	978-9-40-072171-5, 978-9-40-072172-2
Authors	Dominik A. Megger, Nicole Megger, Jens Müller, Megger, Dominik A., Megger, Nicole, Müller, Jens
Abstract	Metal-mediated base pairs are transition metal complexes formed from complementary nucleosides within nucleic acid double helices. Instead of relying on hydrogen bonds, they are stabilized by coordinative bonds. The nucleosides acting as ligands do not necessarily have to be artificial. In fact, several examples are known of naturally occurring nucleobases (e.g., thymine, cytosine) capable of forming stable metal-mediated base pairs that are highly selective towards certain metal ions. This chapter provides a comprehensive overview of metal-mediated base pairs formed from natural nucleosides or from closely related artificial nucleosides that are pyrimidine or purine derivatives. It addresses the different strategies that lead to the development of these base pairs. The article focuses on structural models for metal-mediated base pairs, their experimental characterization within a nucleic acid, and on their possible applications.

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Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
Unknown	6	100%

Demographic breakdown

Readers by professional status	Count	As %
Student > Ph. D. Student	3	50%
Researcher	1	17%
Unknown	2	33%

Readers by discipline	Count	As %
Chemistry	2	33%
Physics and Astronomy	1	17%
Immunology and Microbiology	1	17%
Unknown	2	33%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2021.

All research outputs

#7,451,284

of 22,780,165 outputs

Outputs from Metal ions in life sciences

#47

of 134 outputs

Outputs of similar age

#127,752

of 400,602 outputs

Outputs of similar age from Metal ions in life sciences

of 22 outputs

Altmetric has tracked 22,780,165 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.

So far Altmetric has tracked 134 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.

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We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

Interplay between Metal Ions and Nucleic Acids

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