Staphylococcus aureus
Springer International Publishing
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Timeline
Mendeley readers
| Chapter title |
Cell Wall-Anchored Surface Proteins of Staphylococcus aureus : Many Proteins, Multiple Functions
|
|---|---|
| Chapter number | 5002 |
| Book title |
Staphylococcus aureus
|
| Published in |
Current topics in microbiology and immunology, January 2015
|
| DOI | 10.1007/82_2015_5002 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-972061-6, 978-3-31-972063-0
|
| Authors |
Joan A. Geoghegan, Timothy J. Foster, Geoghegan, Joan A., Foster, Timothy J. |
| Abstract |
Staphylococcus aureus persistently colonizes about 20 % of the population and is intermittently associated with the remainder. The organism can cause superficial skin infections and life-threatening invasive diseases. The surface of the bacterial cell displays a variety of proteins that are covalently anchored to peptidoglycan. They perform many functions including adhesion to host cells and tissues, invasion of non-phagocytic cells, and evasion of innate immune responses. The proteins have been categorized into distinct classes based on structural and functional analysis. Many surface proteins are multifunctional. Cell wall-anchored proteins perform essential functions supporting survival and proliferation during the commensal state and during invasive infections. The ability of cell wall-anchored proteins to bind to desquamated epithelial cells is important during colonization, and the binding to fibrinogen is of particular significance in pathogenesis. |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 73 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 16% |
| Researcher | 10 | 14% |
| Student > Master | 10 | 14% |
| Student > Bachelor | 6 | 8% |
| Student > Postgraduate | 4 | 5% |
| Other | 9 | 12% |
| Unknown | 22 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 13 | 18% |
| Immunology and Microbiology | 13 | 18% |
| Agricultural and Biological Sciences | 11 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Medicine and Dentistry | 2 | 3% |
| Other | 6 | 8% |
| Unknown | 25 | 34% |