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Antibody-Drug Conjugates and Immunotoxins

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Cover of 'Antibody-Drug Conjugates and Immunotoxins'

Table of Contents

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    Book Overview
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    Chapter 1 Antibody Directed Delivery for Treatment of Cancer: Antibody Drug Conjugates and Immunotoxins
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    Chapter 2 Antibody–Drug Conjugate Development
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    Chapter 3 Assay Methodologies and Challenges
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    Chapter 4 Clinical Pharmacology Strategies in the Development of Antibody–Drug Conjugates
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    Chapter 5 Predictive Biomarkers for Antibody–Drug Conjugates
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    Chapter 6 Factors Involved in the Design of Cytotoxic Payloads for Antibody–Drug Conjugates
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    Chapter 7 Linker Technology and Impact of Linker Design on ADC Properties
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    Chapter 8 Antibody–Drug Conjugates for the Treatment of B-Cell Malignancies
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    Chapter 9 Targeting CD19 with SAR3419, an anti-CD19-Maytansinoid Conjugate for the Treatment of B Cell Malignancies
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    Chapter 10 Brentuximab Vedotin (SGN-35) for CD30-Positive Malignancies
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    Chapter 11 Trastuzumab Emtansine (T-DM1) for the Treatment of HER2-Positive Cancer with a Focus on Breast Cancer
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    Chapter 12 CDX-011 (Glembatumumab Vedotin, CR011-vcMMAE)
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    Chapter 13 Case Study: An Antibody–Drug Conjugate Targeting MUC16 for Ovarian Cancer
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    Chapter 14 EphA2 Immunoconjugate
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    Chapter 15 Anti-PSMA Antibody-Drug Conjugates and Immunotoxins
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    Chapter 16 Targeting CD56 (NCAM)-Expressing Neoplasms with Lorvotuzumab Mertansine
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    Chapter 17 Studies on the Metabolism of Antibody–Drug Conjugates
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    Chapter 18 Design, Development, and Characterization of Recombinant Immunotoxins Targeting HER2/neu
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    Chapter 19 The Preclinical and Clinical Evaluation of VB6-845: An Immunotoxin with a De-Immunized Payload for the Systemic Treatment of Solid Tumors
Attention for Chapter 5: Predictive Biomarkers for Antibody–Drug Conjugates
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Chapter title
Predictive Biomarkers for Antibody–Drug Conjugates
Chapter number 5
Book title
Antibody-Drug Conjugates and Immunotoxins
Published by
Springer, New York, NY, January 2013
DOI 10.1007/978-1-4614-5456-4_5
Book ISBNs
978-1-4614-5455-7, 978-1-4614-5456-4
Authors

David Dornan, Jeff Settleman, Dornan, David, Settleman, Jeff

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 1 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 100%
Student > Master 1 100%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 1 100%
Immunology and Microbiology 1 100%