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Antibody-Drug Conjugates and Immunotoxins

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Cover of 'Antibody-Drug Conjugates and Immunotoxins'

Table of Contents

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    Book Overview
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    Chapter 1 Antibody Directed Delivery for Treatment of Cancer: Antibody Drug Conjugates and Immunotoxins
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    Chapter 2 Antibody–Drug Conjugate Development
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    Chapter 3 Assay Methodologies and Challenges
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    Chapter 4 Clinical Pharmacology Strategies in the Development of Antibody–Drug Conjugates
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    Chapter 5 Predictive Biomarkers for Antibody–Drug Conjugates
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    Chapter 6 Factors Involved in the Design of Cytotoxic Payloads for Antibody–Drug Conjugates
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    Chapter 7 Linker Technology and Impact of Linker Design on ADC Properties
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    Chapter 8 Antibody–Drug Conjugates for the Treatment of B-Cell Malignancies
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    Chapter 9 Targeting CD19 with SAR3419, an anti-CD19-Maytansinoid Conjugate for the Treatment of B Cell Malignancies
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    Chapter 10 Brentuximab Vedotin (SGN-35) for CD30-Positive Malignancies
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    Chapter 11 Trastuzumab Emtansine (T-DM1) for the Treatment of HER2-Positive Cancer with a Focus on Breast Cancer
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    Chapter 12 CDX-011 (Glembatumumab Vedotin, CR011-vcMMAE)
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    Chapter 13 Case Study: An Antibody–Drug Conjugate Targeting MUC16 for Ovarian Cancer
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    Chapter 14 EphA2 Immunoconjugate
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    Chapter 15 Anti-PSMA Antibody-Drug Conjugates and Immunotoxins
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    Chapter 16 Targeting CD56 (NCAM)-Expressing Neoplasms with Lorvotuzumab Mertansine
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    Chapter 17 Studies on the Metabolism of Antibody–Drug Conjugates
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    Chapter 18 Design, Development, and Characterization of Recombinant Immunotoxins Targeting HER2/neu
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    Chapter 19 The Preclinical and Clinical Evaluation of VB6-845: An Immunotoxin with a De-Immunized Payload for the Systemic Treatment of Solid Tumors
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Title
Antibody-Drug Conjugates and Immunotoxins
Published by
Springer New York, December 2012
DOI 10.1007/978-1-4614-5456-4
ISBNs
978-1-4614-5455-7, 978-1-4614-5456-4
Editors

Phillips, Gail Lewis

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 19%
Student > Master 4 19%
Student > Bachelor 3 14%
Lecturer > Senior Lecturer 1 5%
Other 1 5%
Other 1 5%
Unknown 7 33%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 3 14%
Biochemistry, Genetics and Molecular Biology 3 14%
Agricultural and Biological Sciences 3 14%
Chemistry 2 10%
Immunology and Microbiology 1 5%
Other 2 10%
Unknown 7 33%