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Oxygen Radicals in Biology and Medicine

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Table of Contents

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    Book Overview
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    Chapter 1 Introduction to Peroxidation and Antioxidation Mechanisms
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    Chapter 2 The Redox Thermodynamics for Dioxygen Species (O 2 , O 2 - ·, HOO·, HOOH, and HOO - ) and Monooxygen Species (O, O -· , ·OH, and - OH) in Water and Aprotic Solvents
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    Chapter 3 Electron Spin Resonance Investigations of Oxygen-Centered Free Radicals in Biological Systems
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    Chapter 4 Superoxide Chemistry in Non-Aqueous Media
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    Chapter 5 Peroxy Radicals and Singlet Oxygen ( 1 O 2 ) from the Addition of Superoxide Ion (O 2 - ·) to CCl 4 , CF 3 CCl 3 , PhCCl 3 , N-BuBr and N-BuCl in Acetonitrile
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    Chapter 6 The Uniqueness Both of Superoxide Toxicity and of the Protective Role of Superoxide Dismutase
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    Chapter 7 Peroxyl Radicals in Aqueous Media
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    Chapter 8 Aspects of the HO 2 · Elimination Reaction from Organic Peroxyl Radicals: Some Recent Examples
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    Chapter 9 Kinetic Studies of Alkoxyl Radicals
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    Chapter 10 Radical-Induced Degradation of Organic Halogen and Sulfur Compounds in Oxygenated Aqueous Solutions
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    Chapter 11 Thiyl Free Radical Metabolites of Thiol Drugs and Glutathione
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    Chapter 12 Oxidation of Quinones by H 2 O 2 : Formation of Epoxy- and Hydroxyquinone Adducts and Electronically Excited States
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    Chapter 13 From Nitric Oxide to Desferal: Nitrogen Free Radicals and Iron in Oxidative Injury
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    Chapter 14 Singlet Oxygen: Current Mechanistic Aspects of Photo-Oxidation
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    Chapter 15 Homolysis of Substituted Anisoles: Substituent Effects on Phenoxyl Radical Stabilities
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    Chapter 16 Redox Properties of Oxy and Antioxidant Radicals
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    Chapter 17 The Role of Metals in Aqueous Superoxide Chemistry
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    Chapter 18 Fenton Chemistry Revisited: Amino Acid Oxidation
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    Chapter 19 Iron Redox Reactions and Lipid Peroxidation
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    Chapter 20 The Generation of Ferryl or Hydroxyl Radicals During Interaction of Hemeproteins with Hydrogen Peroxide
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    Chapter 21 The Production of Hydroxyl and Semiquinone Free Radicals During the Autoxidation of Redox Active Flavonoids
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    Chapter 22 Fenton Reactions in Lipid Phases: Iron Solubility, Oh Production, and Initiation of Lipid Oxidation
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    Chapter 23 The Role of Hemoglobin in Generating Oxyradicals
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    Chapter 24 Specific Detection of Lipid Hydroperoxides Using HPLC-EC Method
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    Chapter 25 Quantitative Determination of Fatty Acid Hydroperoxides in Vivo
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    Chapter 26 Detection of Lipid Peroxidation Products in Lipids and Tissues by Gas Chromatography-Mass Spectrometry
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    Chapter 27 Direct Chemical Ionization Mass Spectrometry of Underivatized Arachidonic Acid Metabolites: Application to Leukotriene Biosynthesis
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    Chapter 28 Chemiluminescence — High Performance Liquid Chromatography of Phosphatidylcholine Hydroperoxide in Human Blood Plasma
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    Chapter 29 Method for Tracing Oxygen-18 in Vivo: Application to Ozone Dosimetry in Animals
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    Chapter 30 Malondialdehyde Derivatives in Urine
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    Chapter 31 Electron Spin Resonance of The Semiquinone of The Antitumor Antibiotic Streptonigrin and Its Metal Complexes
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    Chapter 32 The Detection of Singlet Oxygen in Biochemical Systems Using 1268 nm Chemiluminescence
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    Chapter 33 Phagocyte Dioxygenation Reactions Yielding Chemiluminescence: The Maximum Multiplicity and Spin Conservation Rules Relative to Oxygen Reactivity
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    Chapter 34 Bryostatin stimulation of human neutrophil luminol and DBA (lucigenin) chemiluminescence.
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    Chapter 35 Luciferase Reverse Micellar Bioluminescence: Kinetics and Emission Spectra
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    Chapter 36 Platelet Chemiluminiscence Induced by Linoleic and Arachidonic Acids
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    Chapter 37 Low Level Chemiluminescence from Isolated Rat Hepatocytes, Intact Lung and Intestine in situ
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    Chapter 38 Prevention by Propionylcarnitine of NADPH and Tert-Butyl Hydroperoxide-Dependent Chemiluminescence in Heart Microsomes
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    Chapter 39 Chemiluminescence from Vitamin E-Deficient Erythrocyte Membranes Induced by Xanthine Oxidase Reaction
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    Chapter 40 Monitoring the Interactions of Environmental Agents by Cell-Dependent Chemiluminescence: Studies with Polycyclic Aromatic Hydrocarbons
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    Chapter 41 Gel State Chemiluminescence: An Artificial Electron Transport System
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    Chapter 42 Hydroperoxidation of Unsaturated Fatty Esters
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    Chapter 43 Lipid Peroxidation and Retinal Phototoxic Degeneration
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    Chapter 44 Production and Metabolism of Cytotoxic Phospholipids Generated during Incubation of Liposomes with Oxyhemoglobin
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    Chapter 45 Lipid Peroxidation Dependent on Oxygen and Catalytic Free Iron Ions in Situ Storage Muscle Foods
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    Chapter 46 A Unique Role of Histidine in Fe-Catalyzed Lipid Oxidation by Fish Sarcoplasmic Reticulum
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    Chapter 47 Cholesterol Epoxidations by Defined Oxygen Species
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    Chapter 48 Thermal Decomposition of Methyl Linoleate and Methyl Linolenate Hydroperoxides Analyzed by Capillary Gas Chromatography
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    Chapter 49 Effect of Dietary Lipid Peroxides on Lymphoid Tissues
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    Chapter 50 Implication of Protein Oxidation in Protein Turnover, Aging, and Oxygen Toxicity
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    Chapter 51 Role of oxidative modification in the lability of ceruloplasmin.
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    Chapter 52 The oxidative modification of lens proteins.
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    Chapter 53 Degradation of the Proteoglycans of Human Articular Cartilage by Reactive Oxygen Metabolites
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    Chapter 54 Free Radical Denaturation of Immunoglobulin G is due to Amino Acid Oxidation: Implications for Rheumatoid Arthritis
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    Chapter 55 A Study of ROS Induced Denaturation of IgG3 Using Monoclonal Antibodies; Implications for Inflammatory Joint Disease
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    Chapter 56 Oxy Radical-Initiated Protein S-Thiolation and Enzymic Dethiolation
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    Chapter 57 Modification of Human Low Density Lipoprotein by Lipid Peroxidation
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    Chapter 58 Is Oxidized Low Density Lipoprotein Involved in the Recruitment and Retention of Monocyte/Macrophages in the Artery Wall during the Initiation of Atherosclerosis?
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    Chapter 59 Copper and Copper-Nicotinic Acid Complexes Mediated Oxidation of High Density Lipoprotein
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    Chapter 60 Oxidation of Human Low Density Lipoprotein Initiated by Copper(II)Chloride
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    Chapter 61 Isolation and Partial Characterization of an Oxidized LDL in Humans
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    Chapter 62 Coronary Disease: Spectroscopic Correlation of Structure and Size of Plasma Lipoproteins with Patient Clinical History
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    Chapter 63 The Effect of Oxygen on the OH Radical-Induced Strand Break Formation of DNA In Vitro and In Vivo
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    Chapter 64 Double Strand Breakage in DNA and Cellular Radiation Sensitivity: Linear Energy Transfer and the Oxygen Effect
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    Chapter 65 Effect of OH scavenging on the yield of radiation-induced DNA double-strand breaks in isolated nuclei.
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    Chapter 66 Sonochemistry of Nucleic Acid Constituents in Aqueous Solution: A Spin-Trapping Study
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    Chapter 67 Gamma Radiolysis of RNA: An ESR and Spin-Trapping Study
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    Chapter 68 Interactions of oxygen and sulfhydryls with free radicals in irradiated mammalian cells.
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    Chapter 69 Oxygen Radicals, Lipid Peroxidation and DNA Damage in Mitochondria
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    Chapter 70 Involvement of Reactive Oxygen Intermediates in the Mutagenicity of Tumor Promoters
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    Chapter 71 Oxidative Damage to DNA in Adrenocortical Cells During Senescence in Culture
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    Chapter 72 Substituted Phthalocyanines as Photodynamic Sensitizers
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    Chapter 73 Effects of Singlet Oxygen on the Biological Activity of DNA and Its Involvement in Single Strand-Break Formation
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    Chapter 74 Determination of 8-Hydroxydeoxyguanosine in Human Urine: a Possible Assay for in Vivo Oxidative DNA Damage
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    Chapter 75 Urine Biomarkers for Oxidative DNA Damage
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    Chapter 76 The Generation of Radicals during the Normal and Abnormal Functioning of Cytochromes P-450
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    Chapter 77 Radical Intermediates in the Catalytic Cycles of Cytochrome P-450
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    Chapter 78 Cytochrome P-450 Model Systems: Alkene Oxidation
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    Chapter 79 Cytochrome P-448 Induction Restores the Propagation of •O 2 - -Induced Lipid Peroxidation in Hepatoma Microsomes
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    Chapter 80 Generation of Superoxide by the Microsomal Mixed-Function Oxidase System
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    Chapter 81 Membrane Permeability and Oxidant Induced Injury
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    Chapter 82 The Measurement of Protein Degradation in Response to Oxidative Stress
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    Chapter 83 Oxidative Modification of Enzymes During Aging and Acute Oxidative Stress
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    Chapter 84 Oxidative Modification of Glutamine Synthetase: Covalent and Conformational Changes Which Control Susceptibility to Proteolysis
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    Chapter 85 Role of Hemin in Oxidative Stress Induced by Divicine in Vitamin E-Deficient Rats
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    Chapter 86 The Isolation and Partial Characterization of Stable H 2 O 2 -Resistant Variants of Chinese Hamster Fibroblasts
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    Chapter 87 Reactive Oxygen Metabolites and Hyperoxic Toxicity
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    Chapter 88 Inhibition of Peroxidation of Membranes
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    Chapter 89 Cellular Protection Against Damage by Hydroperoxides: Role of Glutathione
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    Chapter 90 A Secondary Antioxidant Defense Role for Proteolytic Systems
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    Chapter 91 Radioprotection of Mice with Ascorbic Acid, Desferal and Mercaptoethylamine
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    Chapter 92 Antiinflammatory, Analgesic, and Antiulcer Activities of Copper Complexes Suggest Their Use in a Physiologic Approach to Treatment of Arthritic Diseases
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    Chapter 93 Tocopherol Behavior and Membrane Constituents in Erythrocytes with Oxidant Stress
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    Chapter 94 Porcine Stress Syndrome, Free Radicals and Vitamin E
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    Chapter 95 Increased oxidation of tocopherols in chickens with inherited muscular dystrophy.
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    Chapter 96 Vitamin E and Immune Functions
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    Chapter 97 Beneficial Effect of Dietary Antioxidants on the Aging Immune System
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    Chapter 98 Inclusion of Antioxidants in Resuscitation Fluids
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    Chapter 99 Serum Antioxidant Activity as a Determinant of Pulmonary Dysfunction in Cigarette Smokers
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    Chapter 100 Probing enzyme-substrate recognition and catalytic mechanism in Cu,Zn superoxide dismutase.
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    Chapter 101 Bacterial Superoxide Dismutases
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    Chapter 102 Extracellular-Superoxide Dismutase Association with Cell Surface-Bound Sulfated Glucosaminoglycans
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    Chapter 103 Catalases—With and Without Heme
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    Chapter 104 Glutathione Peroxidase
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    Chapter 105 The Role of Glutathione Transferase in the Detoxication and Repair of Lipid and DNA Hydroperoxides
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    Chapter 106 n-3 Fatty Acids and Hydroperoxide Activation of Fatty Acid Oxygenases
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    Chapter 107 Sequence of Complementary DNA Encoding Human Extracellular-Superoxide Dismutase and Production of Recombinant Enzyme
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    Chapter 108 A cSOD-Null Mutant of Drosophila Confers Sensitivity to Paraquat and Reduced Longevity
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    Chapter 109 Induction of Superoxide Dismutase Activity by Paraquat or Edu in Human Gingival Fibroblasts
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    Chapter 110 Superoxide Dismutase in Cultured Benign and Malignant Tumors of the Colon
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    Chapter 111 Microinjection of Antioxidant Enzymes to Protect Cells from Oxygen Derived Free Radicals
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    Chapter 112 Human Fibroblast Antioxidant Defense Response to Alteration in Oxygen Tension
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    Chapter 113 Relationship Between the Antioxidant Enzyme DT-Diaphorase and Tumor Response to Mitomycin C Treatment
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    Chapter 114 Microsomal Fatty Acid Composition and Ca 2+ Uptake Modifications Induced by Sod Depletion in Rat Liver
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    Chapter 115 The Use of Oxygen Free Radical Scavengers in the Rat Peritonitis Model
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    Chapter 116 Adaptations to Plant Pro-Oxidants in a Phytophagous Insect Model: Enzymatic Protection from Oxidative Stress
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    Chapter 117 Mechanisms for the Generation of Oxygen Radicals by Drugs
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    Chapter 118 Enhancement of chemical activation via radical-dependent mechanisms: an emerging concept in chemical-chemical interactions.
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    Chapter 119 Roles of Oxygen and Oxygen Substitutes in DNA Sugar Damage by Antitumor Antibiotics
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    Chapter 120 Reduction of 5-Nitroimidazoles, Nitrofurazone, and 2,4-Dinitrophenol to their Free Radical Metabolites by Tritrichomonas Foetus Hydrogenosomes
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    Chapter 121 Role of Free Radicals in Etoposide (Vp-16,213) Action
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    Chapter 122 The Mechanism of Quinone Formation from Carcinogenic Benzo[a]Pyrene Mediated by Lipid Peroxidation in Liposomal Suspension
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    Chapter 123 Lipid Peroxidation, Protein Thiols and Calcium Homeostasis in Bromobenzene-Induced Liver Damage
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    Chapter 124 Vanadate Stimulation of Pyridine Nucleotide Oxidation in Mammalian Liver Microsomal Membranes
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    Chapter 125 Mechanism of Oxidation of 1-Methyl-4-Phenyl-3,3-Dihydropyridinium (MPDP + )
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    Chapter 126 Reduction of Nitroheterocyclic Drugs by Ascorbate and Catecholamines: A Possible Mechanism for the Neurotoxicity of Nitroheterocyclic Drugs
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    Chapter 127 Role of Active Oxygen in Paraquat and 1-Methyl-4-phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Cytotoxicity
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    Chapter 128 Free Radical Formation by Cytotoxic Alkylaminoanthraquinones in Liver Microsomes
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    Chapter 129 Lipid Peroxidation and Haloalkylation in CCl 4 -Induced Liver Fatty Degeneration and Necrosis
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    Chapter 130 Paraquat-Resistant HeLa Cells
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    Chapter 131 The respiratory burst oxidase.
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    Chapter 132 Reactions of Myeloperoxidase with Superoxide and Hydrogen Peroxide: Signficance for its Function in the Neutrophil
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    Chapter 133 Bacterial Killing by Phagocytes: Potential Role(s) of Hypochlorous Acid and Hydrogen Peroxide in Protein Turnover, DNA Synthesis, and RNA Synthesis
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    Chapter 134 Cellular Targets of H 2 O 2 and HOCl Induced Injury
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    Chapter 135 Oxidative Modification of Enzymes by Stimulated Neutrophils
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    Chapter 136 Oxidative Inactivation of Neutrophil Granule Proteinases: Implications for Neutrophil-Mediated Proteolysis
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    Chapter 137 Effects of Alpha, Beta-Unsaturated Aldehydes on Macrophage and Neutrophil Membrane Function, Fluidity and Sulfhydryl Status
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    Chapter 138 Latex Beads as Vehicles for the Study of Free Radical Processes in Phagocytic Cells
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    Chapter 139 Superoxide Generation of Phagocytizing Polymorphonuclear Leukocytes from Patients with Chronic Renal Failure
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    Chapter 140 Clastogenic Factor in Ischemia-Reperfusion Injury: Protective Effect of Allopurinol
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    Chapter 141 Inactivation of Creatine Phosphokinase by Superoxide during Reperfusion Injury
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    Chapter 142 The Post Treatment Experiment: An Operational Definition of Reperfusion Injury
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    Chapter 143 Mechanisms of Oxidant-Mediated Microvascular Injury Following Reperfusion of the Ischemic Intestine
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    Chapter 144 The Amplificative Role of PAF-Acether in the Oxidative Stress Following Reperfusion of Ischemic Stomach
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    Chapter 145 Equieffective Protection by Human and Bovine SOD Against Renal Reperfusion Damage in Rats
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    Chapter 146 Potential of Methylene Blue to Block Oxygen Radical Generation in Reperfusion Injury
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    Chapter 147 Superoxide Radical Release into the Cytoplasm of Heart Cells by an NADH-Driven Oxygen Activator
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    Chapter 148 Detection and Measurement of Free Radical Generation during Cardiovascular Injury
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    Chapter 149 Evidence that free radicals result in reperfusion injury in heart muscle.
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    Chapter 150 Identification of Free Radical Species in the Myocardium
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    Chapter 151 Abnormal Electrical Activity Induced by H 2 O 2 in Isolated Canine Myocytes
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    Chapter 152 Role of Oxygen Radicals in Endotoxin Shock and Disseminated Intravascular Coagulation
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    Chapter 153 Plasma Lipid Peroxidation and Atherosclerosis in Restricted Ovulator Chickens
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    Chapter 154 Enzymatic Lipid Peroxidation: A Step in the Breakdown of Mitochondria during the Maturation of Red Blood Cells
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    Chapter 155 Myocardial Salvage by the Free Radical Scavenging Actions of Xanthine Oxidase Inhibitors
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    Chapter 156 Oxygen Radical Scavengers and Myocardial Preservation during Transplantation: Role of Xanthine Oxidase
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    Chapter 157 Endothelial Cells: A Source and Target of Oxidant Damage
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    Chapter 158 The role of iron in injury of endothelial cells in vitro and in vivo.
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    Chapter 159 Alterations in Cultured Rat Pulmonary Artery Endothelial Cells with Hyperoxia; Effect of Age
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    Chapter 160 Lung Energy Metabolism Following Twenty-Four Hours Exposure to One Hundred Percent Oxygen
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    Chapter 161 Prostaglandins and Leukotrienes in Pulmonary O 2 Toxicity
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    Chapter 162 Lipid Peroxidation, Free Radicals and Experimental Inflammation
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    Chapter 163 Inhibition by Prostacyclin Analogs of ·O 2 - Production in Human Polymorphonuclear Leukocytes
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    Chapter 164 Kawasaki Disease, Oxygen Radicals and High Dose Gammaglobulin Therapy
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    Chapter 165 An endogenous source of the superoxide anion in the central nervous system.
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    Chapter 166 Hydrogen Peroxide Production in Dopamine Neurons
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    Chapter 167 Oxygen Radical-Mediated Damage to Brain Tissue
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    Chapter 168 Oxygen-Induced Retinopathy in the Rat
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    Chapter 169 Selective Inhibition of Membrane Atpases by Hydrogen Peroxide in the Lens of the Eye
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    Chapter 170 Anterior Chamber Hydrogen Peroxide: Effects of 3-Aminotriazole on Peroxide Kinetics and on the Status of Glutathione
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    Chapter 171 Morphological Sequelae of Anterior Segment Hydrogen Peroxide in Young and Adult Rabbits with or Without 3-Aminotriazole Treatment
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    Chapter 172 Corneal Oxygen Scavenging Systems: Lysis of Corneal Epithelial Cells by Superoxide Anions
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    Chapter 173 The Role of Allopurinol and Oxygen Free Radical Scavengers in Liver Preservation
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    Chapter 174 Prevention of Acute Renal Failure by SOD and Sucrose
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    Chapter 175 The Aging Process
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    Chapter 176 Influence of Life-Prolonging Food Restriction on Membrane Lipoperoxidation and Antioxidant Status
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Title
Oxygen Radicals in Biology and Medicine
Published by
Springer US, March 2013
DOI 10.1007/978-1-4684-5568-7
ISBNs
978-1-4684-5570-0, 978-1-4684-5568-7
Editors

Simic, Michael G., Taylor, Karen A., Ward, John F., Sonntag, Clemens

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Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 33%
Student > Doctoral Student 2 22%
Student > Bachelor 1 11%
Student > Master 1 11%
Researcher 1 11%
Other 0 0%
Unknown 1 11%
Readers by discipline Count As %
Chemistry 2 22%
Agricultural and Biological Sciences 2 22%
Chemical Engineering 1 11%
Sports and Recreations 1 11%
Materials Science 1 11%
Other 0 0%
Unknown 2 22%