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Structural Genomics and Drug Discovery

Overview of attention for book
Cover of 'Structural Genomics and Drug Discovery'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Data Management in the Modern Structural Biology and Biomedical Research Environment
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    Chapter 2 Structural Genomics of Human Proteins
  4. Altmetric Badge
    Chapter 3 Target Selection for Structural Genomics of Infectious Diseases
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    Chapter 4 Selecting Targets from Eukaryotic Parasites for Structural Genomics and Drug Discovery
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    Chapter 5 High-throughput cloning for biophysical applications.
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    Chapter 6 Expression and solubility testing in a high-throughput environment.
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    Chapter 7 Protein Production for Structural Genomics Using E. coli Expression
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    Chapter 8 Eukaryotic Expression Systems for Structural Studies
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    Chapter 9 Automated Cell-Free Protein Production Methods for Structural Studies
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    Chapter 10 Parallel Protein Purification
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    Chapter 11 Oxidative Refolding from Inclusion Bodies
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    Chapter 12 High-Throughput Crystallization Screening
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    Chapter 13 Screening Proteins for NMR Suitability
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    Chapter 14 Salvage or Recovery of Failed Targets by In Situ Proteolysis
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    Chapter 15 Salvage of Failed Protein Targets by Reductive Alkylation
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    Chapter 16 Salvage or Recovery of Failed Targets by Mutagenesis to Reduce Surface Entropy
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    Chapter 17 Data collection for crystallographic structure determination.
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    Chapter 18 Structure Determination, Refinement, and Validation
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    Chapter 19 Virtual high-throughput ligand screening.
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    Chapter 20 Ligand Screening Using Fluorescence Thermal Shift Analysis (FTS)
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    Chapter 21 Ligand Screening Using Enzymatic Assays
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    Chapter 22 Ligand Screening Using NMR
  24. Altmetric Badge
    Chapter 23 Screening Ligands by X-ray Crystallography
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    Chapter 24 Case study-structural genomics and human protein kinases.
Attention for Chapter 24: Case study-structural genomics and human protein kinases.
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  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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Chapter title
Case study-structural genomics and human protein kinases.
Chapter number 24
Book title
Structural Genomics and Drug Discovery
Published in
Methods in molecular biology, March 2014
DOI 10.1007/978-1-4939-0354-2_24
Pubmed ID
Book ISBNs
978-1-4939-0353-5, 978-1-4939-0354-2
Authors

Elkins JM, Jonathan M. Elkins, Elkins, Jonathan M.

Abstract

A brief summary is made of some of the methods in structural genomics and drug discovery as they apply to protein kinases.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 33%
Researcher 1 33%
Other 1 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 33%
Computer Science 1 33%
Agricultural and Biological Sciences 1 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2014.
All research outputs
#15,308,698
of 22,768,097 outputs
Outputs from Methods in molecular biology
#5,319
of 13,090 outputs
Outputs of similar age
#131,358
of 221,407 outputs
Outputs of similar age from Methods in molecular biology
#33
of 146 outputs
Altmetric has tracked 22,768,097 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,090 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 221,407 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 146 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.