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Host Defense Dysfunction in Trauma, Shock and Sepsis

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Cover of 'Host Defense Dysfunction in Trauma, Shock and Sepsis'

Table of Contents

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    Book Overview
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    Chapter 1 Progress in Trauma Care Through Understanding the Cell Biology of Injury
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    Chapter 2 Trauma, Sepsis, and Immune Defects
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    Chapter 3 Clinical Factors Influencing Host Defense Integrity
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    Chapter 4 The Intensive Care Unit of Tomorrow
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    Chapter 5 How the Immune System Discriminates Infectious Nonself from Noninfectious Self
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    Chapter 6 Signal Transduction Mechanisms: Pathophysiologic Alterations
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    Chapter 7 Neuroendocrine Regulation of Immune Function
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    Chapter 8 Beneficial Effects of Stress Response Blockade on Patients Undergoing Surgery
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    Chapter 9 The Impact of Preexisting Disease Conditions for Host Defense Integrity in Traumatized and Critically Ill Patients
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    Chapter 10 Oxygen Radical-Mediated Endothelial Cell Injury
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    Chapter 11 Characteristics of Neutrophil Dysfunction
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    Chapter 12 Endothelial Dysfunction as an Early Critical Event in Ischemia and Shock
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    Chapter 13 Role of Oxidants, Proinflammatory Agents, and Granulocytes in the Post Ischemic Intestine
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    Chapter 14 Hepatic Parenchymal and Nonparenchymal Cells in Hemorrhage and Ischemia
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    Chapter 15 Acute Lung Injury Following Shock and Major Trauma
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    Chapter 16 Hemorrhage-Induced Alterations in Cell-Mediated Immune Function
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    Chapter 17 Sepsis and Multiple Organ Failure: The Result of Whole Body Inflammation
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    Chapter 18 Multiple Organ Failure (MOF), and Whole Body Inflammation After Multiple Trauma
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    Chapter 19 Neutrophils, Cytokines, Oxygen Radicals, and Lung Injury
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    Chapter 20 The Role of β 2 -Leukocyte Integrins In Vivo
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    Chapter 21 The “Angry” Macrophage and Its Impact on Host Response Mechanisms
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    Chapter 22 Eicosanoids, Cytokines and Altered Metabolic Control in the Evolution of the Posttraumatic Host Defense Failure Syndromes: Adult Respiratory Distress Syndrome and Multiple Organ Failure Syndrome
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    Chapter 23 Diagnostic Role of New Mediators and Markers of Inflammation in Multiple Injured Patients
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    Chapter 24 Intravascular Activation of Polymorphonuclear Neutrophils in Critically Ill Anergic Patients
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    Chapter 25 Mediators of Remote Lung Injury
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    Chapter 26 Immunologic Dyshomeostasis in Multiple Organ Failure: The Gut-Liver Axis
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    Chapter 27 Tumor Necrosis Factor and Other Cytokines as Mediators of Clinical Sepsis
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    Chapter 28 The Protein C System in Septic Shock
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    Chapter 29 Leukocyte-Endothelial Interactions in Trauma and Sepsis
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    Chapter 30 Role of Oxygen Radicals in Multiple Organ Failure
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    Chapter 31 Arachidonic Acid Metabolism in Endotoxemia and Sepsis: Therapeutic Approaches
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    Chapter 32 Biology and Function of Cytotoxic T-Cells
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    Chapter 33 Immune Response to Heat Shock Proteins
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    Chapter 34 Prostaglandins Mediate the Expression of a 72-kDa Heat Shock Protein in Human Fibroblasts
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    Chapter 35 Glucocorticoid-Immune System Interactions in Injury and Sepsis
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    Chapter 36 Hemorrhagic Shock Inhibits Myelopoiesis Independent of Bacterial Translocation
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    Chapter 37 Monocyte HLA-DR Antigen Expression: Its Reproducibility in Asymptomatic Volunteers and Correlation with Clinical Infection
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    Chapter 38 Phenotypic and Functional Characteristics of Peripheral Blood Lymphocytes in a Defined Group of Polytrauma Patients
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    Chapter 39 Cell-Mediated Immunity During and After Cardiopulmonary Bypass
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    Chapter 40 Alterations in Function and Phenotype of Monocytes from Patients with Septic Disease: Predictive Value and New Therapeutic Strategies
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    Chapter 41 Effects of Exercise on the Immune System with Special Reference to Natural Killer Cells
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    Chapter 42 Interaction of Immune, Interferon, and Opioid Systems in Professional Athletes
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    Chapter 43 White Cells in Burn Patients
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    Chapter 44 Fibronectin Degradation: An In Vitro Model of Neutrophil-Mediated Endothelial Cell Damage
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    Chapter 45 Adenosine Inhibits Postischemic Leukocyte Adherence to the Endothelium of Postcapillary Venules via A 2 Receptor
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    Chapter 46 Prostaglandin E 1 Inhibits the Stimulation of Neutrophils In Vitro and In Vivo and Improves Cardio-Respiratory Functions in Multiply Traumatized Patients at Risk of Adult Respiratory Distress Syndrome
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    Chapter 47 Production and Characterization of Peptide-Specific Monoclonal Antibodies that Recognize a Neoepitope on Hog C5a
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    Chapter 48 The Oxidative Burst Reaction of Neutrophils Is Reduced by the Acute Phase Serum Amyloid-A Protein
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    Chapter 49 Interaction of Pentoxifylline and Adenosine in the Inhibition of Superoxide Anion Production of Human Polymorphonuclear Leukocytes
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    Chapter 50 Adhesive Interactions of Neutrophils with Endothelial Cells
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    Chapter 51 Endothelial Cell Stimulation by Anti-CD9 Antibodies
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    Chapter 52 Decrease in Leukotriene Synthesis from Leukocytes Isolated in Septic Patients
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    Chapter 53 Aggravation of Ischemia-Reperfusion Injury in the Striated Muscle Microcirculation by Acute Endotoxemia
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    Chapter 54 Selective Inhibition of Polymorphonuclear Leukocyte Oxidative Burst and CD11b/CD16 Expression by Prostaglandin E 2
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    Chapter 55 The Role of Lysosomal Cysteine Proteinases as Markers of Macrophage Activation and as Nonspecific Mediators of Inflammation
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    Chapter 56 Endothelin Mediates a Ca 2+ Activation Signal in Human Monocytes
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    Chapter 57 Nitric Oxide Synthesis in Sponge Matrix Allografts Coincides with the Initiation of the Allogeneic Response
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    Chapter 58 Neutrophil Elastase Induces Lung Injury Following Lower Limb Ischaemia
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    Chapter 59 PMN Elastase in Local Infection
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    Chapter 60 Opioids from Immune Cells Interact with Receptors on Sensory Nerves to Inhibit Nociception in Inflammation
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    Chapter 61 An In Vitro Model of Hepatic Failure in Septic Shock
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    Chapter 62 Ischemia-Reperfusion Injury of the Liver: Role of Neutrophils and Xanthine Oxidase
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    Chapter 63 Nitric Oxide Regulates Prostaglandin E 2 Release by Rat Kupffer Cells
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    Chapter 64 C3a and C5a in Liver Transplantations during Bypass, Reperfusion, and the Postoperative Phase
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    Chapter 65 Effect of Superoxide Dismutase on Altered Hepatic Calcium Regulation During Gramnegative Sepsis
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    Chapter 66 Role of Liver Macrophages (Kupffer Cells) in Bacterial Cell Wall-Induced Hepatic Inflammation
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    Chapter 67 Tumor Necrosis Factor Alpha Inhibits Hepatocyte Mitochondrial Respiration and Induces Release of Cytoplasmic Enzymes
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    Chapter 68 Modulation of Hepatic Mitochondrial Fat Oxidation and Hepatic Gene Transcription by Tumor Necrosis Factor
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    Chapter 69 Increased Leukocyte Adhesion in Liver Sinusoids Following Superior Mesenteric Artery Occlusion in the Rat
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    Chapter 70 Gene Knockout: New Approach to the Physiology of Cytokines
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    Chapter 71 The Role of Interleukin-1 and Other Macrophage-Derived Cytokines in Macrophage-T-Cell Interactions
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    Chapter 72 Interleukin-1-Induced Hypotension and the Effect of an Interleukin-1 Receptor Antagonist
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    Chapter 73 Interleukin-8 (Neutrophil-Activating Peptide-1) and Related Chemotactic Cytokines
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    Chapter 74 Cellular and Molecular Mechanisms that Regulate the Production of Interleukin-8: The Potential Role of Chemotactic Cytokines in Acute Respiratory Distress Syndrome and Multiple Organ Failure
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    Chapter 75 Generation and Properties of Neutrophil-Activating Peptide 2 (NAP-2)
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    Chapter 76 Soluble and Cell Surface Receptors for Tumor Necrosis Factor
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    Chapter 77 Regulation of Cytokine Synthesis Through Cyclic Nucleotides
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    Chapter 78 Removal of Circulating Cytokines by Hemodialysis Membranes In Vitro
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    Chapter 79 Modulation of Monokine Production In Vitro by Human Intravenous Immunoglobulin
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    Chapter 80 Transforming Growth Factor β 1 Upregulates the Interleukin-2 Receptor α Promoter
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    Chapter 81 Interactions of Immunopathological Mediators (Tumor Necrosis Factor- α , TGF- β , Prostaglandin E 2 ) in Traumatized Individuals
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    Chapter 82 In Vitro Production and Secretion of Interleukin-1 by Human Monocytes After Surgical Trauma
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    Chapter 83 The Biological Characteristics of Cytokines and Their Interactions with Prostaglandins Following Hemorrhagic Shock
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    Chapter 84 The Response of Interleukin-1 and Interleukin-6 in Patients Undergoing Major Surgery
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    Chapter 85 Possible Role of Cytokines in the Stress Response of the Hypothalamo-Pituitary-Adrenal Axis During Upper Abdominal Surgery
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    Chapter 86 The Synthesis of Stress Proteins in Cultured Cardiac Myocytes Is Induced by the Interleukins and Tumor Necrosis Factor
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    Chapter 87 Effects of Tumor Necrosis Factor on the Hypothalamic-Pituitary-Adrenal Axis
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    Chapter 88 Interleukin-2-Modulated Cytokine Secretion in Thermally Injured Patients
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    Chapter 89 Cytokine Treatment of Radiation-Induced Hemopoietic Suppression: Results of Interleukin-6 and Granulocyte Colony-Stimulating Factor in a Murine Radiation Model
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    Chapter 90 Circulating Tumour Necrosis Factor in Active Inflammatory Bowel Disease
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    Chapter 91 Interleukin-1 and Tumor Necrosis Factor- α Suppress Hypoxia-Induced Production of Erythropoietin In Vitro
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    Chapter 92 Neopterin, Interferon- γ , and Immunodeficiency States
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    Chapter 93 Systemic Cytokine Response to Strenuous Exercise
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    Chapter 94 Activation of Neutrophils by Tumor Necrosis Factor- α During Sepsis
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    Chapter 95 Distinct Subpopulations of Human Peripheral Blood Monocytes Characterized by Absence of the CD14 Surface Marker, and Distinguished by High or Low Intracellular Glutathione
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    Chapter 96 The Role of Endotoxins in Burns: Anomalies in Cytokine Regulation of Immunity
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    Chapter 97 Role of Tumor Necrosis Factor on Pseudomonas aeruginosa Infection and on Antitumor Activity in Relation to Arachidonic Cascade
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    Chapter 98 Survival from Cecal Ligation and Puncture and the Formation of Fibrous Adhesions in the Peritoneal Cavity Depend on Endogenous Tumor Necrosis Factor
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    Chapter 99 The Cellular Mechanisms of Tumor Necrosis Factor-Induced Mortality: A Possible Role for Platelet Activating Factor and/or the Eicosanoids
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    Chapter 100 Molecular Mechanisms of Lipopolysaccharide-Induced Cytokine Production by Monocytes
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    Chapter 101 Natural Endotoxic Shock Protection by Soluble CD14
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    Chapter 102 Use of Monophosphoryl Lipid A as a Prophylactic for Sepsis and Shock
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    Chapter 103 Hemodynamic and Pulmonary Response to Treatment with On-Line Adsorption on Polymyxin B During Endotoxemia in Pigs
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    Chapter 104 Apolipoprotein A-I-Enriched Lipoprotein Attenuates Tumor Necrosis Factor Production and Shock in an Anesthetized Rabbit Endotoxemia Model
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    Chapter 105 Escherichia coli -Induced Septic Shock in the Baboon: An Animal Model for the Evaluation of Neutralising Monoclonal Antibodies to Phospholipase A 2
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    Chapter 106 Leukotriene Inhibitor and Antagonist Prevent Endotoxin Lethality in Carrageenan-Pretreated Mice
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    Chapter 107 Effect of Type-Specific Antiserum on the Pulmonary Hypertensive Response to Group B Streptococcus in Piglets
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    Chapter 108 Detection of IgE Reactive With Lipopolysaccharide in Plasma of Traumatically Injured Patients
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    Chapter 109 Altered Guanine Nucleotide Protein Function: Potential Role in Endotoxin Tolerance
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    Chapter 110 The Pattern of Organ Failure Following Severe Trauma-A Postmortem Study
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    Chapter 111 Hypertonic Volume Therapy: A Feasible Regimen to Contribute to the Prevention of Multiple Organ Failure?
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    Chapter 112 A New Sepsis Scale for Burns: Correlation with Endotoxin and Host Response
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    Chapter 113 Multiple Organ Failure: Clinical Characteristics of Gut-Origin Septic States
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    Chapter 114 Intraperitoneal Infections and Multiple Organ Failure
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    Chapter 115 The Role of Empirical Laparotomy in the Management of Sepsis and Multisystem Organ Failure
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    Chapter 116 Management of the Wound as Therapy for Multiple Organ Failure
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    Chapter 117 Aggressive Enteral Nutrition Reduces Sepsis in the Hypercatabolic Injured Patient
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    Chapter 118 Clinical-Mediator Correlations of Multiple Organ Failure and Preventive/Therapeutic Strategies: To Block, Stimulate, or Replace? That is the Question
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    Chapter 119 Bacterial Translocation Following Major Thermal Injury in Rats, Sheep, and Mini-Pigs
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    Chapter 120 Does Early Portal Bacteremia/Endotoxemia Prime for Postinjury Multiple Organ Failure?
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    Chapter 121 Prevention of Bacterial Translocation with Early Enteral Feeding—A Feasible Approach?
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    Chapter 122 Gut-Derived Infectious-Toxic Shock Syndrome: Therapeutic Chances with Polyspecific Immunoglobulins
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    Chapter 123 Maintenance of Gastrointestinal Integrity after Burn Injury with Specific Dietary Supplementation and Epidermal Growth Factor
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    Chapter 124 Selective Decontamination of the Digestive Tract: Open Questions and Controversies
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    Chapter 125 Selective Decontamination of the Digestive Tract (SDD): Review of Available Clinical Studies
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    Chapter 126 Nonselective Gut Decontamination for Avoidance of Bacterial Translocation in Shock
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    Chapter 127 Antibiotics and Phagocytic Cell Function: A Critical Review
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    Chapter 128 Interaction of Antibiotics with the Phagocyte Oxidative Burst
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    Chapter 129 Intraphagocytic Cell Penetration and Intracellular Bioactivity of Antibiotics
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    Chapter 130 Extraphagocytic Killing of Bacteria in the Presence of Antibiotics
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    Chapter 131 Cell Wall Inhibitors and Bacterial Susceptibility to Phagocytosis
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    Chapter 132 Protein Synthesis Inhibitors and Bacterial Susceptibility to Phagocytosis
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    Chapter 133 Augmentation of Host Defense Reactivity with Special Nutrients
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    Chapter 134 The Role of Structured Lipids in Host Defense Interactions
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    Chapter 135 Manipulation of Cytokine Synthesis Through Dietary Lipids
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    Chapter 136 Dietary Fish Oil Prevents Postischemic Leukocyte/Endothelium Interaction Through Inhibition of Leukotriene Biosynthesis
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    Chapter 137 Dietary Requirement for Preformed Purine and Pyrimidine Bases for Intact Function of Cellular Immune Response: A Review
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    Chapter 138 Relationship of Plasma Acute-Phase Protein to Amino Acid Levels During High-Dose Branched Chain Amino Acid Support in Sepsis
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    Chapter 139 Wound Management and the Stress Response
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    Chapter 140 The Role of the Wound in Posttraumatic Immune Dysfunction
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    Chapter 141 The Role of Growth Factors in the Regulation of Wound Repair
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    Chapter 142 An Adverse Wound Environment Reduces Leukocyte Phagocytosis and Protein Synthesis
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    Chapter 143 Basic Fibroblast Growth Factor Inhibits the Release of Oxygen Radicals by Human Granulocytes
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    Chapter 144 The Influence of Liver Regeneration on Skin Wound Healing and Lymphocyte Growth Features
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    Chapter 145 Therapy of Secondary T-Cell Immunodeficiencies with Biological Substances and Drugs: An Update
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    Chapter 146 Progress in Antiinfective Perioperative Immunomodulatory Therapy with Simultaneous Administration of Blocking and Enhancing Agents
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    Chapter 147 Effect of Immunomodulation on Skin Test Reactivity Following Trauma
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    Chapter 148 Therapeutic Use of Cytokines: Animal Models
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    Chapter 149 The Rationale for Gamma-Interferon Administration in Trauma Patients
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    Chapter 150 Immunomodulators of the Thermal Injury Response
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    Chapter 151 Antiendotoxic Therapy with Polyclonal and Polyvalent Immunoglobulins: In Vitro and In Vivo Studies
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    Chapter 152 The Use of Polyvalent Immunoglobulin G in Patients with Sepsis and Multiple Organ Failure
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    Chapter 153 Clinical Effects of Immunoglobulin Administration in Patients with Major Burn Injury
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    Chapter 154 Treatment of Gram-Negative Septic Toxic Diseases with an Immunoglobulin Preparation Containing IgG, IgM and IgA: A Prospective Randomized Clinical Trial
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    Chapter 155 Immunotherapeutic Strategies for Passive Immunization Against Pseudomonas aeruginosa
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    Chapter 156 Binding Characteristics of the Antiendotoxin Antibody Xomen-E5 to Bacterial Whole-Cell Antigens
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    Chapter 157 Immunotherapy with Human Antiendotoxin Antibodies in the Treatment of Gram-Negative Sepsis: Practical Considerations
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    Chapter 158 The Use of Antibody Specificity and Affinity in Determining the Protectiveness of Human Monoclonal Antibodies Against Fatal Infections with Nosocomial Gram-Negative Bacteria
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    Chapter 159 Potential Benefits of Platelet Activating Factor Receptor Antagonists in Endotoxemia/Sepsis
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    Chapter 160 Phospholipase A 2 : A New Target for Monoclonal Antibody Therapy in Sepsis
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    Chapter 161 Administration of Antiadhesion Molecules: A Feasible Approach?
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    Chapter 162 Local Administration of Interleukin-2 Protects Mice from Lethal Intra-Abdominal Bacterial Sepsis
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    Chapter 163 Murine Intraabdominal Abscess: Immune Modulation with Interferon- γ
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    Chapter 164 Acute Resuscitation and Antioxidant Therapy
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    Chapter 165 Clinical Indications for the Administration of Oxygen Radical Scavengers
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    Chapter 166 First Experiences with Recombinant Human Superoxide Dismutase Therapy in Polytraumatized Patients
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Title
Host Defense Dysfunction in Trauma, Shock and Sepsis
Published by
Springer Berlin Heidelberg, December 2012
DOI 10.1007/978-3-642-77405-8
ISBNs
978-3-64-277407-2, 978-3-64-277405-8
Editors

Faist, Eugen, Meakins, Jonathan L., Schildberg, Friedrich W.

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Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 20%
Professor > Associate Professor 1 20%
Student > Bachelor 1 20%
Unknown 2 40%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 40%
Pharmacology, Toxicology and Pharmaceutical Science 1 20%
Unknown 2 40%