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Drug Discovery and Evaluation: Methods in Clinical Pharmacology

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Cover of 'Drug Discovery and Evaluation: Methods in Clinical Pharmacology'

Table of Contents

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    Book Overview
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    Chapter 1 General Introduction
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    Chapter 2 Introduction
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    Chapter 3 Dose Finding in Single Dose Studies by Allometric Scaling
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    Chapter 4 Multiple Dose Studies
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    Chapter 5 Dose Linearity and Proportionality
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    Chapter 6 Effects of Food Intake
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    Chapter 7 Special Populations: Profiling the Effect of Obesity on Drug Disposition and Pharmacodynamics
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    Chapter 8 Special Populations: Renal Impairment
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    Chapter 9 Special Populations: Hepatic Impairment
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    Chapter 10 Special Populations: Protein Binding Aspects
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    Chapter 11 The Human ADME Study
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    Chapter 12 Synthesis of Radiolabeled Compounds for Clinical Studies
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    Chapter 13 Drug–Drug Interaction Studies
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    Chapter 14 In Vitro/In Vivo Correlation for Drug–Drug Interactions
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    Chapter 15 Specific Studies for Formulation Development
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    Chapter 16 Absolute and Relative Bioavailability
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    Chapter 17 Bioequivalence
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    Chapter 18 Population Pharmacokinetics in Clinical Pharmacology
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    Chapter 19 Bioanalysis of Clinical Studies
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    Chapter 20 Biomarker Definition and Validation During Drug Development
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    Chapter 21 Toxicokinetics and Safety Ratios
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    Chapter 22 In Vitro/In Vivo Correlation for Transporters
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    Chapter 23 Relevance of Transporters in Clinical Studies
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    Chapter 24 Specificities for Oncology Studies
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    Chapter 25 Pharmacogenomics in and its Influence on Pharmacokinetics
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    Chapter 26 PK/PD Approaches
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    Chapter 27 Methodologies of PD Assessment: Scales
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    Chapter 28 Methodologies of Pharmacodynamic Assessment
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    Chapter 29 Pharmacodynamic Drug–Drug Interactions
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    Chapter 30 Methodologies of Safety Assessment in Clinical Pharmacology
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    Chapter 31 Pharmacodynamic Evaluation: Cardiovascular Methodologies
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    Chapter 32 Pharmacodynamic Evaluation: CNS
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    Chapter 33 Pharmacodynamic Evaluation: Diabetes Methodologies
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    Chapter 34 Pharmacodynamic Evaluation: Inflammation/Immunology
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    Chapter 35 Pharmacodynamic Evaluation: Endocrinology
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    Chapter 36 Pharmacodynamic Evaluation: Dermatology
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    Chapter 37 Pharmacodynamic Evaluation: Oncology
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    Chapter 38 Development of Regulations for Submitting Pharmacogenomic Data to Authorities
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    Chapter 39 Pharmacogenomic-Guided Drug Development
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Title
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Published by
Springer Berlin Heidelberg, February 2011
DOI 10.1007/978-3-540-89891-7
ISBNs
978-3-54-089890-0, 978-3-54-089891-7
Editors

Vogel, Hans Gerhard, Maas, Jochen, Gebauer, Alexander

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 1%
Canada 1 1%
Unknown 96 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 18%
Researcher 16 16%
Student > Bachelor 12 12%
Student > Master 8 8%
Other 7 7%
Other 15 15%
Unknown 22 22%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 23 23%
Medicine and Dentistry 15 15%
Agricultural and Biological Sciences 11 11%
Chemistry 5 5%
Engineering 4 4%
Other 15 15%
Unknown 25 26%