↓ Skip to main content

Behavioral Neurogenetics

Overview of attention for book
Cover of 'Behavioral Neurogenetics'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 178 Behavioural Genetics of Childhood Disorders.
  3. Altmetric Badge
    Chapter 179 Rare Genomic Deletions and Duplications and their Role in Neurodevelopmental Disorders
  4. Altmetric Badge
    Chapter 180 Using Zebrafish to Unravel the Genetics of Complex Brain Disorders
  5. Altmetric Badge
    Chapter 181 Behavioral Genetics of Neurodegenerative Disorders.
  6. Altmetric Badge
    Chapter 182 Toward a Mechanistic Understanding of How Variability in Neurobiology Shapes Individual Differences in Behavior.
  7. Altmetric Badge
    Chapter 183 Schizophrenia Genes: On the Matter of Their Convergence.
  8. Altmetric Badge
    Chapter 184 Gene × Environment Interaction Models in Psychiatric Genetics
  9. Altmetric Badge
    Chapter 185 Behavioral Genetics of Affective and Anxiety Disorders
  10. Altmetric Badge
    Chapter 186 Behavioural Genetics of the Serotonin Transporter.
  11. Altmetric Badge
    Chapter 187 Genetic Factors Modulating the Response to Stimulant Drugs in Humans
  12. Altmetric Badge
    Chapter 188 The Cognitive Genetics of Neuropsychiatric Disorders
  13. Altmetric Badge
    Chapter 189 Forward Genetic Approaches to Understanding Complex Behaviors
  14. Altmetric Badge
    Chapter 190 Mouse Models of the 5-HTTLPR × Stress Risk Factor for Depression
  15. Altmetric Badge
    Chapter 191 Behavioral and Pharmacogenetics of Aggressive Behavior
  16. Altmetric Badge
    Chapter 192 Selectively Bred Rodents as Models of Depression and Anxiety
  17. Altmetric Badge
    Chapter 193 Stress-Induced Deficits in Cognition and Emotionality: A Role for Glutamate
  18. Altmetric Badge
    Chapter 194 Susceptibility Genes for Schizophrenia: Mutant Models, Endophenotypes and Psychobiology
  19. Altmetric Badge
    Chapter 195 Genetic Models of Sensorimotor Gating: Relevance to Neuropsychiatric Disorders
  20. Altmetric Badge
    Chapter 196 Applications of Second Generation Sequencing Technologies in Complex Disorders
Attention for Chapter 195: Genetic Models of Sensorimotor Gating: Relevance to Neuropsychiatric Disorders
Altmetric Badge

Mentioned by

googleplus
1 Google+ user

Citations

dimensions_citation
2 Dimensions

Readers on

mendeley
88 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Genetic Models of Sensorimotor Gating: Relevance to Neuropsychiatric Disorders
Chapter number 195
Book title
Behavioral Neurogenetics
Published in
Current topics in behavioral neurosciences, May 2013
DOI 10.1007/7854_2011_195
Pubmed ID
Book ISBNs
978-3-64-227858-7, 978-3-64-227859-4
Authors

Susan B. Powell, Martin Weber, Mark A. Geyer, Powell, Susan B., Weber, Martin, Geyer, Mark A.

Abstract

Sensorimotor gating, or the ability of a sensory event to suppress a motor response, can be measured operationally via prepulse inhibition (PPI) of the startle response. PPI is deficient in schizophrenia patients as well as other neuropsychiatric disorders, can be measured across species, and has been used widely as a translational tool in preclinical neuropharmacological and genetic research. First developed to assess drug effects in pharmacological and developmental models, PPI has become one of the standard behavioral measures in genetic models of schizophrenia and other neuropsychiatric disorders that exhibit PPI deficits. In this chapter we review the literature on genetic models of sensorimotor gating and discuss the utility of PPI as a tool in phenotyping mutant mouse models. We highlight the approaches to genetic mouse models of neuropsychiatric disease, discuss some of the important caveats to these approaches, and provide a comprehensive table covering the more recent genetic models that have evaluated PPI.

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 1%
United States 1 1%
Germany 1 1%
Switzerland 1 1%
Unknown 84 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 31%
Researcher 16 18%
Student > Bachelor 6 7%
Student > Master 6 7%
Student > Doctoral Student 5 6%
Other 15 17%
Unknown 13 15%
Readers by discipline Count As %
Neuroscience 20 23%
Agricultural and Biological Sciences 14 16%
Medicine and Dentistry 13 15%
Psychology 7 8%
Biochemistry, Genetics and Molecular Biology 6 7%
Other 11 13%
Unknown 17 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 May 2013.
All research outputs
#2,016,965
of 3,628,597 outputs
Outputs from Current topics in behavioral neurosciences
#56
of 103 outputs
Outputs of similar age
#44,196
of 85,237 outputs
Outputs of similar age from Current topics in behavioral neurosciences
#1
of 1 outputs
Altmetric has tracked 3,628,597 research outputs across all sources so far. This one is in the 25th percentile – i.e., 25% of other outputs scored the same or lower than it.
So far Altmetric has tracked 103 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 85,237 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them