Advances in Dementia Research

Table of Contents

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   Book Overview
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   Chapter 1 White matter changes: the clinical consequences in the aging population
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   Chapter 2 Longitudinal change of white matter abnormalities
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   Chapter 3 Genetic aspects of microangiopathy-related cerebral damage
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   Chapter 4 Research criteria for subcortical vascular dementia in clinical trials
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   Chapter 5 How can cerebral infarcts and hemorrhages lead to dementia?
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   Chapter 6 Vascular aspects in Alzheimer’s disease
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   Chapter 7 Novel imaging technologies in the assessment of cerebral ageing and vascular dementia
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   Chapter 8 Alzheimer disease and neuroinflammation
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    Chapter 9 The immunological microenvironment in the CNS: implications on neuronal cell death and survival
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    Chapter 10 Toxic effector molecules in the pathogenesis of immune-mediated disorders of the central nervous system
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    Chapter 11 Cytokines in CNS disorders: neurotoxicity versus neuroprotection
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    Chapter 12 Do neuronal inclusions kill the cell?
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    Chapter 13 Mechanisms of cell death in neurodegenerative disorders
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    Chapter 14 Estrogens, apoptosis and cells of neural origin
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    Chapter 15 Markers of apoptosis and models of programmed cell death in Alzheimer’s disease
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    Chapter 16 Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease
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    Chapter 17 Genetics of Alzheimer’s disease — routes to the pathophysiology
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    Chapter 18 Secretion of the amyloid precursor protein is elevated isoform specifically by apolipoprotein E4
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    Chapter 19 Alterations in neurotrophins and neurotrophin receptors in Alzheimer’s disease
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    Chapter 20 Genetically altered transgenic models of Alzheimer’s disease
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    Chapter 21 Morphological substrates of mental dysfunction in Lewy body disease: an update
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    Chapter 22 Mechanism of neurofibrillary degeneration and pharmacologic therapeutic approach
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    Chapter 23 Understanding the role of estrogen on cognition and dementia
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    Chapter 24 Present and future of Alzheimer therapy
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    Chapter 25 Trials to slow progression and prevent disease onset
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    Chapter 26 Epidemiologic clues to the causes and routes to prevention of Alzheimer disease
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    Chapter 27 Post-transcription modulation of the blood-brain barrier GLUT1 glucose transporter by brain-derived factors
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    Chapter 28 A brain derived peptide preparation reduces the translation dependent loss of a cytoskeletal protein in primary cultured chicken neurons
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    Chapter 29 Neurotrophic effects of Cerebrolysin ® in animal models of excitotoxicity
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    Chapter 30 Cerebrolysin ® reduces microglial activation in vivo and in vitro: a potential mechanism of neuroprotection
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    Chapter 31 Clinical experience with Cerebrolysin®
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    Chapter 32 Approach towards an integrative drug treatment of Alzheimer’s disease
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    Chapter 33 Oral Cerebrolysin enhances brain alpha activity and improves cognitive performance in elderly control subjects.