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Innovations for Next-Generation Antibody-Drug Conjugates

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Cover of 'Innovations for Next-Generation Antibody-Drug Conjugates'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction: Motivations for Next-Generation ADCs
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    Chapter 2 Combining ADCs with Immuno-Oncology Agents
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    Chapter 3 Improving the Safety Profile of ADCs
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    Chapter 4 Utility of PK-PD Modeling and Simulation to Improve Decision Making for Antibody-Drug Conjugate Development
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    Chapter 5 Regulatory Considerations and Companion Diagnostics
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    Chapter 6 Outlook on Next Generation Technologies and Strategy Considerations for ADC Process Development and Manufacturing
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    Chapter 7 HER2-Targeted ADCs: At the Forefront of ADC Technology Development
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    Chapter 8 Next Generation Payloads for ADCs
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    Chapter 9 Delivering More Payload (High DAR ADCs)
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    Chapter 10 Site-Specific Antibody-Drug Conjugates
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    Chapter 11 Bispecific and Biparatopic Antibody Drug Conjugates
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    Chapter 12 Targeting Drug Conjugates to the Tumor Microenvironment: Probody Drug Conjugates
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    Chapter 13 Antibody-Drug Conjugates: Targeting the Tumor Microenvironment
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    Chapter 14 Next Horizons: ADCs Beyond Oncology
Attention for Chapter 3: Improving the Safety Profile of ADCs
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