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Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain

Overview of attention for book
Attention for Chapter 4: Purinergic and glutamatergic receptors on astroglia.
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Chapter title
Purinergic and glutamatergic receptors on astroglia.
Chapter number 4
Book title
Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain
Published in
Advances in neurobiology, August 2014
DOI 10.1007/978-3-319-08894-5_4
Pubmed ID
Book ISBNs
978-3-31-908893-8, 978-3-31-908894-5
Authors

Verkhratsky A, Burnstock G, Verkhratsky, Alexei, Burnstock, Geoffrey, Alexei Verkhratsky, Geoffrey Burnstock

Abstract

Astroglial cells express many neurotransmitter receptors; the receptors to glutamate and ATP being the most abundant. Here, we provide a concise overview on the expression and main properties of astroglial glutamate receptors (ionotropic receptors represented by AMPA and NMDA subtypes) and metabotropic (mainly mGluR5 and mGluR3 subtypes) and purinoceptors (adenosine receptors of A1, A2A, A2B, and A3 types, ionotropic P2X1/5 and P2X7 subtypes, and metabotropic P2Y purinoceptors). We also discuss the role of these receptors in glial physiology and pathophysiology.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 7%
Unknown 14 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 33%
Professor 3 20%
Other 2 13%
Student > Ph. D. Student 2 13%
Student > Doctoral Student 1 7%
Other 1 7%
Unknown 1 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 33%
Neuroscience 4 27%
Medicine and Dentistry 2 13%
Chemistry 1 7%
Unknown 3 20%