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Farnesyltransferase Inhibitors in Cancer Therapy

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Cover of 'Farnesyltransferase Inhibitors in Cancer Therapy'

Table of Contents

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    Book Overview
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    Chapter 1 Signal Transduction Pathways
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    Chapter 2 The Biochemistry of Farnesyltransferase and Geranylgeranyltransferase I
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    Chapter 3 Structures of Protein Farnesyltransferase
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    Chapter 4 Peptidomimetic-Based Inhibitors of Farnesyltransferase
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    Chapter 5 Antitumor Efficacy of a Farnesyltransferase Inhibitor in Transgenic Mice
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    Chapter 6 Development of Farnesyltransferase Inhibitors as Potential Antitumor Agents
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    Chapter 7 Tricyclic Farnesyl Protein Transferase Inhibitors
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    Chapter 8 Histidylbenzylglycinamides
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    Chapter 9 From Random Screening of Chemical Libraries to the Optimization of FPP-Competitive Inhibitors of Farnesyltransferase
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    Chapter 10 Genetic Analysis of FTase and GGTase I and Natural Product Farnesyltransferase Inhibitors
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    Chapter 11 Effects of Farnesyltransferase Inhibitors on Cytoskeleton, Cell Transformation, and Tumorigenesis
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    Chapter 12 Prenyltransferase Inhibitors as Radiosensitizers
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    Chapter 13 Farnesyltransferase and Geranylgeranyltransferase I Inhibitors as Novel Agents for Cancer and Cardiovascular Diseases
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    Chapter 14 Protein Prenylation in Trypanosomatids
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    Chapter 15 Early Clinical Experience with Farnesyl Protein Transferase Inhibitors
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    Chapter 16 Phase I Trial of Oral R115777 in Patients with Refractory Solid Tumors
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    Chapter 17 Farnesyltransferase and Geranylgeranyltransferase Inhibitors
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Title
Farnesyltransferase Inhibitors in Cancer Therapy
Published by
Humana Press, October 2000
DOI 10.1007/978-1-59259-013-1
ISBNs
978-1-4684-9606-2, 978-1-59259-013-1
Editors

Sebti, Saïd M., Hamilton, Andrew D.