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Immune Responses to Biosurfaces

Overview of attention for book
Cover of 'Immune Responses to Biosurfaces'

Table of Contents

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    Book Overview
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    Chapter 1 Thromboinflammation in Therapeutic Medicine.
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    Chapter 2 Complement Interactions with Blood Cells, Endothelial Cells and Microvesicles in Thrombotic and Inflammatory Conditions
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    Chapter 3 Role of Complement on Broken Surfaces After Trauma.
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    Chapter 4 Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches.
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    Chapter 5 The Lectin Pathway of Complement and Biocompatibility
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    Chapter 6 Foreign Body Reaction to Subcutaneous Implants
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    Chapter 7 Molecular Characterization of Macrophage-Biomaterial Interactions
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    Chapter 8 Heparan Sulfate Proteoglycan Metabolism and the Fate of Grafted Tissues.
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    Chapter 9 Xenotransplantation of Cells, Tissues, Organs and the German Research Foundation Transregio Collaborative Research Centre 127.
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    Chapter 10 Macroencapsulated Pig Islets Correct Induced Diabetes in Primates up to 6 Months.
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    Chapter 11 Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplantation: Points for Therapeutic Interventions.
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    Chapter 12 Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy.
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    Chapter 13 Complement Interception Across Humoral Incompatibility in Solid Organ Transplantation: A Clinical Perspective
Attention for Chapter 10: Macroencapsulated Pig Islets Correct Induced Diabetes in Primates up to 6 Months.
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Chapter title
Macroencapsulated Pig Islets Correct Induced Diabetes in Primates up to 6 Months.
Chapter number 10
Book title
Immune Responses to Biosurfaces
Published in
Advances in experimental medicine and biology, January 2015
DOI 10.1007/978-3-319-18603-0_10
Pubmed ID
26306449
Book ISBNs
978-3-31-918602-3, 978-3-31-918603-0
Authors

Gianello, Pierre, Pierre Gianello

Abstract

A bioartificial pancreas, in which islets of Langerhans are encapsulated within a semipermeable membrane, may be an alternative therapeutic device for diabetic patients. It may constitute another safe and simple method of transplanting islets without the need for immunosuppressive therapy. Since the semipermeable membrane protects the islets from the host immune system, the islets are likely to survive and release insulin for a long period of time, thereby controlling glucose metabolism in the absence of immunosuppressive medication. Recent data using macroencapsulation of pig islets in primate seems encouraging. In fact, a "mono/bilayer" configuration of macroencapsulated pig islets implanted subcutaneously has been found to significantly improve diabetes control in primates for 6 months without any immunosuppression.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 21%
Student > Bachelor 3 16%
Other 2 11%
Researcher 2 11%
Unspecified 1 5%
Other 3 16%
Unknown 4 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 16%
Medicine and Dentistry 3 16%
Agricultural and Biological Sciences 2 11%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Immunology and Microbiology 1 5%
Other 3 16%
Unknown 6 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2015.
All research outputs
#20,290,425
of 22,826,360 outputs
Outputs from Advances in experimental medicine and biology
#3,971
of 4,950 outputs
Outputs of similar age
#295,848
of 353,125 outputs
Outputs of similar age from Advances in experimental medicine and biology
#189
of 272 outputs
Altmetric has tracked 22,826,360 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,950 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,125 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 272 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

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