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Biological Reactive Intermediates III

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Cover of 'Biological Reactive Intermediates III'

Table of Contents

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    Book Overview
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    Chapter 1 Years with Elizabeth and James Miller: in Appreciation
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    Chapter 2 Reactivity and tumorigenicity of bay-region diol epoxides derived from polycyclic aromatic hydrocarbons.
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    Chapter 3 Chemistry of Covalent Binding: Studies with Bromobenzene and Thiobenzamide
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    Chapter 4 Role of Thiols in Protection Against Biological Reactive Intermediates
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    Chapter 5 Role of Parenchymal Versus Non-Parenchymal Cells on the Control of Biologically Reactive Intermediates
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    Chapter 6 Significance of Covalent Binding of Chemically Reactive Metabolites of Foreign Compounds to Proteins and Lipids
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    Chapter 7 Structure and Function of Cytochrome P-450
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    Chapter 8 Antibodies as Probes of Cytochrome P450 Isozymes
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    Chapter 9 Age and Sex Differences in Constitutive Forms of Cytochrome P-450 of Rat Liver Microsomes
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    Chapter 10 Identification of Intratissue Sites for Xenobiotic Activation and Detoxication
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    Chapter 11 Monoclonal Antibody-Directed Analysis of Cytochrome P-450
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    Chapter 12 Drug Interactions with Macrolide Antibiotics: Specificity of Pseudo-Suicide Inhibition and Induction of Cytochrome P-450
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    Chapter 13 Isomeric Composition of N -Alkylated Protoporphyrins Produced by Substituted Dihydropyridines in Vivo and in Vitro
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    Chapter 14 UDP-Glucuronyltransferases and Their Toxicological Significance
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    Chapter 15 Expression and Sequence Analysis of Rat Liver Glutathione S-Transferase Genes
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    Chapter 16 Rat Cytosolic Epoxide Hydrolase
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    Chapter 17 Multiplicity of Cytochrome P-450 in Morris Hepatoma
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    Chapter 18 The Metabolism of Benzene and Phenol by a Reconstituted Purified Phenobarbital-Induced Rat Liver Mixed Function Oxidase System
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    Chapter 19 Comparison of the Metabolism of Benzene and Its Metabolite Phenol in Rat Liver Microsomes
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    Chapter 20 Further Evidence for a Role of Isozymes of P450 in the Metabolism and Toxicity of Carbon Disulfide (CS 2 )
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    Chapter 21 Effect of a Suicide Substrate on the Metabolism of Steroids and Xenobiotics and on Cytochrome P-450 Apoproteins
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    Chapter 22 Activation of Cytochrome P-450 Heme in Vivo
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    Chapter 23 The FAD-Containing Monooxygenase of Lung and Liver Tissue from Rabbit, Mouse and Pig: Species and Tissue Differences
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    Chapter 24 Oxygen Radical Formation During Redox Cycling of Bleomycin-Fe(III) Catalyzed by NADPH-Cytochrome P-450 Reductase of Liver Microsomes and Nuclei
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    Chapter 25 Superoxide Dismutase Modification and Genotoxicity of Transition-Metal Ion Chelators
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    Chapter 26 Toxicologic Implications of the Iron-Dependent Activation of Bleomycin A 2 by Mouse Lung Microsomes
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    Chapter 27 The Peroxidative Activation of Butylated Hydroxytoluene to BHT-Quinone Methide and Stilbenequinone
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    Chapter 28 Activation of Xenobiotics by Human Polymorphonuclear Leukocytes via Reactive Oxygen-Dependent Reactions
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    Chapter 29 Metabolism of Diehtylstilbestrol by Horseradish Peroxidase and Prostaglandin Synthase — Evidence for a Free Radical Intermediate
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    Chapter 30 Thiyl Radicals--Their Generation and Further Reactions
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    Chapter 31 Mechanism of the Cytochrome P-450 Catalyzed Isomerization of Hydroperoxides
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    Chapter 32 Indole-3-carbinol Inhibits Lipid Peroxidation in Cell-Free Systems
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    Chapter 33 Glutathione Peroxidase and Reactive Oxygen Species in TCDD-Induced Lipid Peroxidation
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    Chapter 34 Activation of Nitrosamines to Mutagens by Rat and Rabbit Nasal, Lung and Liver S-9 Homogenates
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    Chapter 35 Structure of the Adduct of Glutathione and Activated 3-Mathylindole
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    Chapter 36 Studies on the Mechanism of S -Cysteine Conjugate Metabolism and Toxicity in Rat Liver, Kidney, and a Cell Culture Model
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    Chapter 37 Formation and Identification of Naphthoquinone Glutathione Conjugates Following Microsomal Metabolism of 1-Naphthol
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    Chapter 38 The Formation of N-Glucuronides Catalyzed by Purified Hepatic 17β-Hydroxysteroid and 3α-Hydroxysteroid UDP-Glucuronyltransferases
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    Chapter 39 Improved Method for Determination of Cellular Thiols, Disulfides and Protein Mixed Disulfides Using HPLC with Electrochemical Detection
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    Chapter 40 Arylsulfotransferase IV Catalyzed Sulfation of 1-Naphthalenemethanol
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    Chapter 41 Activated Phase II Metabolites: Comparison of Alkylation by 1-0-Acyl Glucuronides and Acyl Sulfates
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    Chapter 42 Reactions of Oxaprozin-1-0-Acyl Glucuronide in Solutions of Human Plasma and Albumin
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    Chapter 43 Nephrotoxic Amino Acid and Glutathione S -Conjugates: Formation and Renal Activation
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    Chapter 44 The Role of Glutathione in the Toxicity of Xenobiotic Compounds: Metabolic Activation of 1,2-Dibromoethane by Glutathione
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    Chapter 45 A Comparison of the Alkylating Capabilities of the Cysteinyl and Glutathionyl Conjugates of 1,2-Dichloroethane
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    Chapter 46 Covalent reactions in the toxicity of SO2 and sulfite.
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    Chapter 47 One- and Two-Electron Oxidation of Reduced Glutathione by Peroxidases
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    Chapter 48 Reactive Oxygen Species Formed in Vitro and in Cells: Role of Thiols(GSH). Model Studies with Xanthine Oxidase and Horseradish Peroxidase
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    Chapter 49 Active Oxygen and Toxicity
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    Chapter 50 Studies on the Mechanism of Activation and the Mutagenicity of Ronidazole, a 5-Nitroimidazole
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    Chapter 51 Carcinogen-DNA Adduct Formation as a Predictor of Metabolic Activation Pathways and Reactive Intermediates in Benzidine Carcinogenesis
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    Chapter 52 Purification, Properties and Function of N-Hydroxyarylamine O- Acetyltransferase
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    Chapter 53 Metabolism and Carcinogenicity of Nitrotoluenes
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    Chapter 54 Hydroxylamines and Hemolytic Anemia
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    Chapter 55 Electrophilic Sulfuric Acid Ester Metabolites as Ultimate Carcinogens
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    Chapter 56 Biological Reactive Intermediates of Mycotoxins
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    Chapter 57 Biological Reactive Intermediates of Pyrrolizidine Alkaloids
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    Chapter 58 Mutagens and Carcinogens Formed During Cooking
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    Chapter 59 Quinone Imines as Biological Reactive Intermediates
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    Chapter 60 The Role of Reactive Intermediates in Sulfhydryl-Dependent Immunotoxicity: Interference with Microtubule Assembly and Microtubule-dependent Cell Function
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    Chapter 61 Investigation of the Immunological Basis of Halothane-Induced Hepatotoxicity
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    Chapter 62 Inhibition of RNA Synthesis in Mouse Macrophages and Lymphocytes by Benzene and Its Metabolites
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    Chapter 63 p-Nitrosophenetole: A Reactive Intermediate of Phenacetin that Binds to Protein
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    Chapter 64 Mechanism of Fasting-Induced Suppression of Acetaminophen Glucuronidation in the Rat
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    Chapter 65 Effect of Diethyl Ether on the Bioactivation, Detoxification, and Hepatotoxicity of Acetaminophen in Vitro and in Vivo
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    Chapter 66 Piperonyl Butoxide Reduces Salicylate-Induced Nephrotoxicity and Covalent Binding in Male Rats
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    Chapter 67 Cross-Linking of Protein Molecules by the Reactive Metabolite of Acetaminophen, N -Acetyl- p -Benzoquinone Imine, and Related Quinoid Compounds
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    Chapter 68 Acetaminophen as a cosubstrate and inhibitor of prostaglandin H synthase.
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    Chapter 69 The Fate of 4-Cyanoacetanilide in Rats and Mice: The Mechanism of Formation of a Novel Electrophilic Metabolite
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    Chapter 70 Mechanistic studies of acetamide hepatocarcinogenicity.
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    Chapter 71 Reactions of Glutathione with Oxidative Intermediates of Acetaminophen
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    Chapter 72 Flavin-containing monooxygenase activity in human liver microsomes.
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    Chapter 73 S9-Dependent Activation of 1-Nitropyrene and 3-Nitrofluoranthene in Bacterial Mutagenicity Assays
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    Chapter 74 Formation of a Ring-Opened Product from Benzene in a Hydroxyl Radical Generating System
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    Chapter 75 H-2 Modulation of Aryl Hydrocarbon Hydroxylase Induction and the Mutagenicity of Benzo(a)Pyrene after 3-Methylcholanthrene Treatment
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    Chapter 76 Stereoselectivity of Rat Liver Cytochrome P-450 Isozymes: Direct Determination of Enantiomeric Composition of K-Region Epoxides Formed in the Metabolism of Benz[A]Anthracene and 7,12-Dimethylbenz[A]Anthracene
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    Chapter 77 Induction of Unscheduled DNA Synthesis in Human Mononuclear Leukocytes by Oxidative Stress
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    Chapter 78 Deoxyguanosine Adducts Formed from Benzoquinone and Hydroquinone
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    Chapter 79 3-Hydroxy- Trans -7,8-Dihydro-7,8-Dihydroxy-Benzo(a)Pyrene, a Metabolite of 3-Hydroxybenzo(a)Pyrene
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    Chapter 80 Time Course of the Effect of 4-Hydroperoxycyclophosphamide on Limb Differentiation in Vitro
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    Chapter 81 Hepatic Pathological Changes Due to Hydroxyalkenals
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    Chapter 82 Clofibrate Selectively Induces Azoreduction of Dimethylaminoazobenzene (DAB) by Rat Liver Microsomes
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    Chapter 83 Intracellular Dissipative Structures (IDS) as Ultimate Targets of Chemical Cytotoxicity
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    Chapter 84 Helenalin: mechanism of toxic action.
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    Chapter 85 Evidence for Stereoselective Production of Phenytoin (5,5-Diphenylhydantoin) Arene Oxides in Man
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    Chapter 86 Tissue Distribution and Covalent Binding of [ 14 C]1,1-Dichloroethylene in Mice: In vivo and in vitro Studies
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    Chapter 87 Inhibition of Respiration in Rabbit Proximal Tubules by Bromophenols and 2-Bromohydroquinone
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    Chapter 88 In Vitro Covalent Binding of 14 C-Mibolerone to Rat Liver Microsomes
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    Chapter 89 Chemistry of Metabolites of Thioureas
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    Chapter 90 Conversion of Phenytoin to Reactive Metabolites in Rat Liver Microsomes
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    Chapter 91 Comparison of N-methylformamide-induced hepatotoxicity and metabolism in rats and mice.
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    Chapter 92 Epoxidation of 1,3-Butadiene in Liver and Lung Tissue of Mouse, Rat, Monkey and Man
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    Chapter 93 Enzyme Catalysed Cleavage of the N-N Bond of N-Nitrosamines
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    Chapter 94 Use of the Chemiluminigenic Probes Luminol and Lucigenin for the Detection of Active Oxygen Species in Hepatic Microsomes and in Intact Hepatocytes
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    Chapter 95 Altered Expression of Oncogenes in Mouse Epidermis Following Exposure to Benzo(A)Pyrene Diol Epoxides
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    Chapter 96 Acetaminophen toxicity in isolated hepatocytes.
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    Chapter 97 Mechanism of Organ Specificity in Nitrosamine Carcinogenesis
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    Chapter 98 Biological Reactive Metabolites in Human Toxicity
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    Chapter 99 Metabolic Host Factors as Modifiers of Reactive Intermediates Possibly Involved in Human Cancer
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    Chapter 100 Closing Remarks
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Title
Biological Reactive Intermediates III
Published by
Springer US, December 2012
DOI 10.1007/978-1-4684-5134-4
ISBNs
978-1-4684-5136-8, 978-1-4684-5134-4
Editors

Kocsis, James J., Jollow, David J., Witmer, Charlotte M., Nelson, Judd O., Snyder, Robert

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 67%
Student > Ph. D. Student 1 33%
Readers by discipline Count As %
Medicine and Dentistry 2 67%
Agricultural and Biological Sciences 1 33%