Chapter title |
Peripheral blood lymphocyte subpopulations in multiple myeloma.
|
---|---|
Chapter number | 137 |
Book title |
Function and Structure of the Immune System
|
Published in |
Advances in experimental medicine and biology, January 1979
|
DOI | 10.1007/978-1-4615-9101-6_137 |
Pubmed ID | |
Book ISBNs |
978-1-4615-9103-0, 978-1-4615-9101-6
|
Authors |
Schedel, I, Beck, P, Peest, D, Schneider, K D, Fricke, M, Eckert, G, Deicher, H, Schedel, I., Beck, P., Peest, D., Schneider, K.-D., Fricke, M., Eckert, G., Deicher, H. |
Abstract |
Antisera raised against idiotypic determinants of myeloma proteins and macroglobulins have been used to differentiate peripheral blood lymphocytes populations from individual patients. I.D.-positive lymphocytes not resembling plasma cells have been regularly found in peripheral blood in these diseases. This lymphocyte population is heterogeneous with respect to non-tumor-specific surface markers, such as SRBC-, Fc- and C-receptors. Tumor specific idiotypic determinants will thus allow a more correct recognition of the total tumor cell compartment in these diseases. |
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