Chapter 1 Historical Overview of Chemical Library Design

Chapter 2 Chemoinformatics and Library Design

Chapter 3 Chemical Library Design

Chapter 4 A Scalable Approach to Combinatorial Library Design

Chapter 5 Application of Free–Wilson Selectivity Analysis for Combinatorial Library Design

Chapter 6 Application of QSAR and Shape Pharmacophore Modeling Approaches for Targeted Chemical Library Design

Chapter 7 Combinatorial Library Design from Reagent Pharmacophore Fingerprints

Chapter 8 Docking Methods for Structure-Based Library Design

Chapter 9 Structure-Based Library Design in Efficient Discovery of Novel Inhibitors

Chapter 10 Structure-Based and Property-Compliant Library Design of 11β-HSD1 Adamantyl Amide Inhibitors

Chapter 11 Design of Screening Collections for Successful Fragment-Based Lead Discovery

Chapter 12 Fragment-Based Drug Design

Chapter 13 LEAP into the Pfizer Global Virtual Library (PGVL) Space: Creation of Readily Synthesizable Design Ideas Automatically

Chapter 14 The Design, Annotation, and Application of a Kinase-Targeted Library

Chapter 15 PGVL Hub: An Integrated Desktop Tool for Medicinal Chemists to Streamline Design and Synthesis of Chemical Libraries and Singleton Compounds

Chapter 16 Design of Targeted Libraries Against the Human Chk1 Kinase Using PGVL Hub

Chapter 17 GLARE: A Tool for Product-Oriented Design of Combinatorial Libraries

Chapter 18 CLEVER: A General Design Tool for Combinatorial Libraries