Chapter title |
Notch signaling and ageing.
|
---|---|
Chapter number | 6 |
Book title |
GeNeDis 2014
|
Published in |
Advances in experimental medicine and biology, January 2015
|
DOI | 10.1007/978-3-319-08927-0_6 |
Pubmed ID | |
Book ISBNs |
978-3-31-908926-3, 978-3-31-908927-0
|
Authors |
Eleftheria Polychronidou, Dimitrios Vlachakis, Panayiotis Vlamos, Marc Baumann, Sophia Kossida, Polychronidou, Eleftheria, Vlachakis, Dimitrios, Vlamos, Panayiotis, Baumann, Marc, Kossida, Sophia |
Abstract |
Notch signaling is a master controller of the neural stem cell and neural development maintaining a significant role in the normal brain function. Notch genes are involved in embryogenesis, nervous system, and cardiovascular and endocrine function. On the other side, there are studies representing the involvement of Notch mutations in sporadic Alzheimer disease, other neurodegenerative diseases such as Down syndrome, Pick's and Prion's disease, and CADASIL. This manuscript attempts to present a holistic view of the positive or negative contribution of Notch signaling in the adult brain, and at the same time to present and promote the promising research fields of study. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 4 | 17% |
Other | 2 | 8% |
Student > Doctoral Student | 2 | 8% |
Student > Bachelor | 2 | 8% |
Student > Master | 2 | 8% |
Other | 5 | 21% |
Unknown | 7 | 29% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 6 | 25% |
Medicine and Dentistry | 3 | 13% |
Psychology | 2 | 8% |
Immunology and Microbiology | 1 | 4% |
Computer Science | 1 | 4% |
Other | 1 | 4% |
Unknown | 10 | 42% |