Biochemistry of Vitamin B 6 and PQQ

Table of Contents

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   Book Overview
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   Chapter 1 History of Vitamin B6
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   Chapter 2 Molecular evolution of pyridoxal-5′-phosphate-dependent enzymes
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   Chapter 3 Stereospecificity of aminotransferases for C-4′ hydrogen transfer and enzyme evolution
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   Chapter 4 Detection of weak structural similarities among PLP dependent enzymes
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   Chapter 5 Crystallographic studies on the vitamin B 6 -assisted enzymic transamination reaction
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   Chapter 6 Redesign of aspartate aminotransferase specificity to that of tyrosine aminotransferase
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   Chapter 7 Enzyme-substrate interactions modulating protonation and tautomerization states of the aldimines of pyridoxal enzymes
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   Chapter 8 Functional role of the mobile stretch Gly36-Val37-Gly38 of porcine cytosolic aspartate aminotransferase
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    Chapter 9 Using 1 H-and 15 N-NMR spectroscopy to observe active sites of porcine cytosolic and Escherichia coli aspartate aminotransferases
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    Chapter 10 Aspartate aminotransferases like it hot
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    Chapter 11 Studies on the mechanism of action of D-amino acid transaminase
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    Chapter 12 Cytosolic factors and the twisting path from birth to berth in aspartate aminotransferases
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    Chapter 13 Mitochondrial protein import: role of certain domains of mitochondrial aspartate aminotransferase
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    Chapter 14 Cytosolic aspartate aminotransferase : tissue-specific hormonal regulation of a housekeeping gene promoter
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    Chapter 15 Regulation by glucagon of serine:pyruvate/alanine:glyoxylate aminotransferase gene expression in cultured hepatocytes
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    Chapter 16 Glutamate 1-semialdehyde aminotransferase, a unique enzyme in chlorophyll biosynthesis
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    Chapter 17 Mechanism of glutamate semialdehyde aminotransferase probed with substrate analogues
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    Chapter 18 Crystallographic and kinetic studies of the tryptophan synthase α 2 β 2 complex with a mutation in β subunit lysine-87 that binds pyridoxal phosphate
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    Chapter 19 The Roles of Chemical Transformation, Loop Closure, Tunnel Function and Metal Ion Activation in the Tryptophan Synthase Mechanism
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    Chapter 20 Effects of Monovalent Cations on Functional Properties of the Tryptophan Synthase α 2 β 2 Complex in Solution and in the Crystal
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    Chapter 21 The long-range effect on the mutual activation of the α and β subunits in the α 2 β 2 complex of tryptophan synthase
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    Chapter 22 X-ray Structure, Sequence and Solution Properties of Ornithine Decarboxylase from Lactobacillus 30a
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    Chapter 23 Dialkylglycine decarboxylase structure: alkali metal binding sites and bifunctional active site
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    Chapter 24 The Location and Role of Active-Site Bases in PLP-Dependent Decarboxylase Enzymes as Deduced from Stereochemical and Kinetic Studies
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    Chapter 25 GuCI-induced unfolding of pig kidney dopa decarboxylase: Evidence for a multi-state process
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    Chapter 26 The transition state complex in the phosphorylase catalyzed reaction
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    Chapter 27 Binding mode of glucans to α-glucan phosphorylase isozymes and their chimeric enzymes
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    Chapter 28 Slow conformational transitions of muscle glycogen phosphorylase b
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    Chapter 29 X-ray study of tryptophanase at 2.1 Å resolution
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    Chapter 30 Crystallographic studies of tyrosine phenol-lyase
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    Chapter 31 Studies of the Mechanism of Tyrosine Phenol-lyase: Kinetics and Site-Directed Mutagenesis
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    Chapter 32 The role of pyridoxal phosphate in the refolding of serine hydroxymethyltransferase
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    Chapter 33 The Mechanism of O-Acetylserine Sulfhydrylase from Salmonella typhimurium
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    Chapter 34 Involvement of PLP in biological formation iron-sulfur clusters
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    Chapter 35 Iron-sulfur clusters as alternatives to pyridoxal-5′-phosphate in bacterial L-serine dehydratases: Cloning of the gene encoding the β-subunit of the enzyme from Peptostreptococcus asaccharolyticus
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    Chapter 36 Phosphorescence of Pyridoxal Kinase at Room Temperature: The Effects of Ligands Bound to the Nucleotide Site
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    Chapter 37 The Schiff base of pyridoxal-5′-phospate with ethylenediamine and ethylamine: Species in solution
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    Chapter 38 Biological role and reactivity of TPQ containing amine oxidases
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    Chapter 39 Two distinct quinoprotein amine oxidases are functioning in Aspergillus niger
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    Chapter 40 The catalytic competence of cobalt-amine oxidase
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    Chapter 41 Mechanistic Studies of Copper/Topa Amine Oxidases
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    Chapter 42 Design, synthesis and evaluation of mechanism-based inhibitors of copper amine oxidases
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    Chapter 43 Copper ion-dependent biogenesis of topa quinone cofactor covalently bound to bacterial monoamine oxidase
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    Chapter 44 Modulation of lysyl oxidase activity toward peptidyl lysine by vicinal dicarboxylic amino acid residues
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    Chapter 45 The structure and function of quinoprotein dehydrogenases
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    Chapter 46 Quinoprotein oxidoreductases for the oxidation of alcohols, sugars and amines
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    Chapter 47 The ternary complex between methylamine dehydrogenase, amicyanin and cytochrome c<Subscript>551i</Subscript>
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    Chapter 48 Model studies directed toward the action of quinoprotein methanol dehydrogenase
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    Chapter 49 Nutritional aspects of vitamin B 6 : requirements, recommendations and intake
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    Chapter 50 Vitamin B 6 transport and metabolism: Clues for delivery of bioactive compounds
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    Chapter 51 Vitamin B 6 Modulation of Steroid Receptor-mediated Gene Expression
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    Chapter 52 Pyridoxine (vitamin B 6 ), neurotransmitters and hypertension
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    Chapter 53 A liver enzyme, serine:pyruvate/alanine:glyoxylate aminotransferase and its mutant in a primary hyperoxaluria type 1 case
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    Chapter 54 Pyridoxal Phosphate, GABA and Seizure Susceptibility
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    Chapter 55 Monoclonal antibodies to bovine brain GABA transaminase
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    Chapter 56 Effect of pyrroloquinoline quinone (PQQ) on the SLE-like (Systemic Lupus Erythematosus) disease in MRL-Ipr/Ipr mice
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    Chapter 57 Conclusions