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Drug Discovery and Evaluation

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Cover of 'Drug Discovery and Evaluation'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction to Safety Pharmacology
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    Chapter 2 Status of Safety Pharmacology and Present Guidelines
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    Chapter 3 Central Nervous System (CNS) Safety Pharmacology Studies
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    Chapter 4 Methods in Cardiovascular Safety Pharmacology
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    Chapter 5 Safety Pharmacology of Drugs for the Urinary Tract
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    Chapter 6 Respiratory Function Assays in Safety Pharmacology
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    Chapter 7 Metabolism Pharmacology
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    Chapter 8 Peripheral Nervous System
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    Chapter 9 Safety of Intravenous and Inhalation Anesthetics
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    Chapter 10 Side Effects of Central Analgesic Drugs
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    Chapter 11 Safety Pharmacology of Antiinflammatory Drugs
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    Chapter 12 Safety Pharmacology of Drugs with Osteoarthritis-Related Activity
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    Chapter 13 Safety Pharmacology of Blood Constituents
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    Chapter 14 Ocular Toxicity Tests
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    Chapter 15 Assays in Endocrine Safety Pharmacology
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    Chapter 16 Safety Assays in Skin Pharmacology
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    Chapter 17 Magnetic Resonance Imaging in Pharmaceutical Safety Assessment
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    Chapter 18 Introduction
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    Chapter 19 Physicochemical Properties
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    Chapter 20 In-Silico ADME Modeling
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    Chapter 21 Absorption – in vitro Tests – Cell Based
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    Chapter 22 Absorption – in-vitro Tests – Non-Cell Based
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    Chapter 23 Distribution – in vitro Tests – Protein Binding
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    Chapter 24 Perfused Organs
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    Chapter 25 Metabolism Studies in vitro and in vivo
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    Chapter 26 Distribution – Across Barriers
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    Chapter 27 Drug–Drug Interaction – Enzyme Induction
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    Chapter 28 Drug–Drug Interaction – Enzyme Inhibition
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    Chapter 29 Absorption
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    Chapter 30 In vivo Distribution
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    Chapter 31 Distribution – in vivo – Other Methods
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    Chapter 32 Bioanalytical Assays – Toxicokinetics
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    Chapter 33 Bioanalytical Assays – Liquid Chromatography Coupled to Tandem Mass Spectrometry
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    Chapter 34 Bioanalytical Assays – Gas Chromatography
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    Chapter 35 Bioanalytical Assays – RIA/EIA
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    Chapter 36 Clinical Studies – Typical Designs
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    Chapter 37 Pharmacogenomics in DME
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    Chapter 38 Typical PK/PD Approaches
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    Chapter 39 Population Pharmacokinetics in Drug Development
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    Chapter 40 Introduction
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    Chapter 41 International Guidelines for the Development of Pharmaceutical Compounds
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    Chapter 42 General Toxicity
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    Chapter 43 In Silico Methods
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    Chapter 44 Alternative Methods for Carcinogenity Testing
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    Chapter 45 Genotoxicity
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    Chapter 46 Reproduction Toxicology
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    Chapter 47 Toxicogenomics and Toxicoproteomics
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    Chapter 48 Application of Toxicoproteomics in Profiling Drug Effects
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4 Mendeley
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Title
Drug Discovery and Evaluation
Published by
Springer Berlin Heidelberg, September 2006
DOI 10.1007/3-540-29804-5
ISBNs
978-3-54-025638-0, 978-3-54-029804-5
Editors

Vogel, H. Gerhard, Hock, Franz Jakob, Maas, Jochen, Mayer, Dieter

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 75%
Unknown 1 25%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 2 50%
Medicine and Dentistry 1 25%
Unknown 1 25%