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Statistics Applied to Clinical Trials

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Cover of 'Statistics Applied to Clinical Trials'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Hypotheses, Data, Stratification
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    Chapter 2 The Analysis Of Efficacy Data
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    Chapter 3 The Analysis of Safety Data
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    Chapter 4 Log Likelihood Ratio Tests For Safety Data Analysis
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    Chapter 5 Equivalence Testing
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    Chapter 6 Statistical Power And Sample Size
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    Chapter 7 Interim Analyses
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    Chapter 8 Controlling The Risk of False Positive Clinical Trials
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    Chapter 9 Multiple Statistical Inferences
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    Chapter 10 The Interpretation of The P-Values
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    Chapter 11 Research Data Closer To Expectation Than Compatible With Random Sampling
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    Chapter 12 Statistical Tables For Testing Data Closer To Expectation Than Compatible With Random Sampling
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    Chapter 13 Principles Of Linear Regression
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    Chapter 14 Subgroup Analysis Using Multiple Linear Regression: Confounding, Interaction, Synergism
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    Chapter 15 Curvilinear Regression
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    Chapter 16 Logistic and Cox Regression, Markow Models, Laplace Transformations
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    Chapter 17 Regression Modeling for Improved Precision
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    Chapter 18 Post-Hoc Analyses in Clinical Trials, a Case for Logistic Regression Analysis
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    Chapter 19 Confounding
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    Chapter 20 Interaction
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    Chapter 21 Meta-Analysis, Basic Approach
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    Chapter 22 Meta-Analysis, Review and Update of Methodologies
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    Chapter 23 Crossover Studies with Continuous Variables
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    Chapter 24 Crossover Studies with Binary Responses
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    Chapter 25 Cross-Over Trials Should not be Used to Test Treatments with Different Chemical Class
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    Chapter 26 Quality-of-Life Assessments in Clinical Trials
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    Chapter 27 Statistical Analysis of Genetic Data
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    Chapter 28 Relationship Among Statistical Distributions
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    Chapter 29 Testing Clinical Trials for Randomness
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    Chapter 30 Clinical Trials do not Use Random Samples Anymore
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    Chapter 31 Clinical Data Where Variability is More Important than Averages
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    Chapter 32 Testing Reproducibility
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    Chapter 33 Validating Qualitative Diagnostic Tests
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    Chapter 34 Uncertainty of Qualitative Diagnostic Tests
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    Chapter 35 Meta-Analysis of Diagnostic Accuracy
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    Chapter 36 Validating Quantitative Diagnostic Tests
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    Chapter 37 Summary of Validation Procedures for Diagnostic Tests
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    Chapter 38 Validating Surrogate Endpoints of Clinical Trials
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    Chapter 39 Methods for Repeated Measures Analysis
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    Chapter 40 Advanced Analysis of Variance, Random Effects and Mixed Effects Models
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    Chapter 41 Monte Carlo Methods
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    Chapter 42 Physicians’ Daily Life and the Scientific Method
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    Chapter 43 Clinical Trials: Superiority-Testing
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    Chapter 44 Trend-Testing
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    Chapter 45 Odds Ratios and Multiple Regression Models, Why and How to Use Them
  47. Altmetric Badge
    Chapter 46 Statistics is no “Bloodless” Algebra
  48. Altmetric Badge
    Chapter 47 Bias Due to Conflicts of Interests, Some Guidelines
Overall attention for this book and its chapters
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Title
Statistics Applied to Clinical Trials
Published by
Springer Netherlands, December 2008
DOI 10.1007/978-1-4020-9523-8
ISBNs
978-1-4020-9522-1, 978-1-4020-9523-8
Editors

Cleophas, Ton J., Zwinderman, Aeilko H., Cleophas, Toine F., Cleophas, Eugene P.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 <1%
Ghana 1 <1%
Brazil 1 <1%
Sweden 1 <1%
South Africa 1 <1%
Finland 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 109 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 24 21%
Student > Ph. D. Student 23 20%
Student > Master 13 11%
Other 9 8%
Professor 8 7%
Other 28 24%
Unknown 12 10%
Readers by discipline Count As %
Medicine and Dentistry 31 26%
Agricultural and Biological Sciences 17 15%
Engineering 10 9%
Mathematics 10 9%
Psychology 5 4%
Other 31 26%
Unknown 13 11%