MACPF/CDC Proteins - Agents of Defence, Attack and Invasion

Precise values for #cholesterol activity measurements will allow a more quantitative treatment of the experimental data, which so far have been qualitatively described using terms like "cholesterol accessibility". 2/8 https://t.co/Wi5f1D0su3

Cholesterol-dependent cytolysins (CDCs) constitute a family of pore-forming toxins secreted by Gram-positive bacteria. These toxins form transmembrane pores by inserting a large beta-barrel into cholesterol-containing membrane bilayers. Binding of water...