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Mendeley readers
| Chapter title |
Construction of Multi-Potent MicroRNA Sponge and Its Functional Evaluation
|
|---|---|
| Chapter number | 15 |
| Book title |
MicroRNA and Cancer
|
| Published in |
Methods in molecular biology, January 2018
|
| DOI | 10.1007/978-1-4939-7435-1_15 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7433-7, 978-1-4939-7435-1
|
| Authors |
Suhwan Chang, Chang, Suhwan |
| Abstract |
MicroRNA is a small, endogenous RNA that inhibits specific gene expression by interacting mostly on the UTR region of target mRNA. Among various methods to inhibit the microRNA, microRNA sponge is a construct designed to inhibit specific microRNA by providing excess amount of target mRNA. Here, we describe a method to generate multi-potent miRNA sponge which can inhibit multiple microRNAs simultaneously. In addition, two methods to examine the functionality of miRNA sponge will be introduced. This tool can be used to stably inhibit multiple microRNAs either in cell or in vivo, expanding the scope of functional analysis of specific microRNAs. |
Mendeley readers
The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 7 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 1 | 14% |
| Student > Bachelor | 1 | 14% |
| Student > Ph. D. Student | 1 | 14% |
| Student > Master | 1 | 14% |
| Researcher | 1 | 14% |
| Other | 0 | 0% |
| Unknown | 2 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 57% |
| Unknown | 3 | 43% |