Chapter 1 Toxicogenomics and Classic Toxicology: How to Improve Prediction and Mechanistic Understanding of Human Toxicity

Chapter 2 Use of Traditional End Points and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic Toxicology

Chapter 3 Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications

Chapter 4 Role of Statistics in Toxicogenomics

Chapter 5 Predictive Toxicogenomics in Preclinical Discovery

Chapter 7 Bioinformatics: Databasing and Gene Annotation

Chapter 8 Microarray Probe Mapping and Annotation in Cross-Species Comparative Toxicogenomics

Chapter 9 Toxicogenomics in Biomarker Discovery

Chapter 10 From Pharmacogenomics to Translational Biomarkers

Chapter 11 Public consortium efforts in toxicogenomics.

Chapter 12 Applications of Toxicogenomics to Nonclinical Drug Development: Regulatory Science Considerations