Prions

Table of Contents

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   Book Overview
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   Chapter 1 Pathology of Variant Creutzfeldt-Jakob Disease
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   Chapter 2 Clinical Aspects of Variant CJD
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   Chapter 3 Dura mater related Creutzfeldt-Jakob disease in Japan: Relationship between sites of grafts and clinical features
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   Chapter 4 Treatment Options in Patients with Prion Disease - the Role of Long Term Cerebroventricular Infusion of Pentosan Polysulphate
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   Chapter 5 Human prion diseases: novel diagnostic principles
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   Chapter 6 History and state of the art of PrP-res “typing” in Creutzfeldt-Jakob disease
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   Chapter 7 Chronic Wasting Disease in Cervids in North America
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   Chapter 8 Bovine spongiform encephalopathy (BSE) in Japan
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    Chapter 9 The role of host PrP in control of incubation time
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    Chapter 10 The role of the immune system in TSE agent neuroinvasion
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    Chapter 11 Prion protein interactions and TSE infections in cell culture models
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    Chapter 12 Semi-classical Quantization of Protein Dynamics: Novel NMR Relaxation Formalism and its Application to Prion
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    Chapter 13 Surveillance of chronic wasting disease (CWD) in Japan
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    Chapter 14 Unexpected high incidence of visceral AA-amyloidosis in slaughtered cattle in Japan
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    Chapter 15 A Novel BSE screening kit with simplified preparation method for EIA
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    Chapter 16 Detection of recombinant bovine prion protein by fluorescence correlation spectroscopy
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    Chapter 17 PrPSc distribution of a natural case of bovine spongiform encephalopathy
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    Chapter 18 Report of the first oral inoculation of BSE prion into cattle in Japan
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    Chapter 19 The development of the intracerebral inoculation method and BSE experimental transmissions to calves
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    Chapter 20 Comparative analyses of three mouse-adapted scrapie strains G1, Obihiro, and I3/I5 and pathogenesis of G1 strain-induced polyuria in ICR mice
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    Chapter 21 Dose effect on detection of PrP Sc in follicular dendritic cells of knock-in mice for rapid bioassay
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    Chapter 22 Cell surface retention of PrP C by anti-PrP antibody prevents protease-resistant PrP formation
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    Chapter 23 Prion-conformation-specific human antibodies established from phage display library
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    Chapter 24 Partial characterization of monoclonal antibodies which bind to disease-associated prion protein in immunoprecipitaion assay
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    Chapter 25 Production and Characterization of Monoclonal Antibodies Specific for Prion Protein
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    Chapter 26 In vitro selection of anti-mouse prion protein RNA aptamers
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    Chapter 27 Detection of the Prion Protein in a Liquid Phase Capture Assay Using Magnetic Beads Coupled to Protein A
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    Chapter 28 New pretreatment method for immunohistochemistry for abnormal prion protein
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    Chapter 29 Cellular prion protein suppresses the apoptosis in a neuronal cell line established from type-1 prion protein gene-deficient mice
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    Chapter 30 Cellular prion protein suppressess the apoptotic cell death by mediating the intracellular H 2 O 2 in primary culture and immortalized neuronal cells
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    Chapter 31 Targeting of cytosolic PrP C via a novel 14-3-3-Tom 70-mitochondrial BCL-2 pathway induces mitochondrial apoptosis
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    Chapter 32 Microtubule-dependent intracellular trafficking of cellular prion protein
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    Chapter 33 Hsp90 modifies the conformation of recombinant mouse prion protein in vitro
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    Chapter 34 Purification and characterization of a novel ATP-dependent robust protein-unfoldase, Unfoldin
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    Chapter 35 Nucleic acid and Prion protein interaction produces spherical amyloids which in vivo can function as coats of Spongiform Encephalopathy agent
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    Chapter 36 Species barrier in yeast [PSI + ] prion transmission
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    Chapter 37 Molecular memory of [PSI + ] prion strains in S. cerevisiae is dependent on the primary structure of the Sup35 prion domain
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    Chapter 38 Expression of a splice variant of prion protein during hypoxia in human glioblastoma cell line T98G
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    Chapter 39 PRNP promoter region polymorphism in Creutzfeldt-Jakob disease
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    Chapter 40 Tubulovesicular structures are consistently found in prion diseases including vCJD and FFI
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    Chapter 41 Autophagy is a common ultrastructural feature of neuropathology of prion diseases
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    Chapter 42 Type 1 and type 2 human PrP Sc have different aggregation sizes in methionine homozygotes with sporadic, iatrogenic and variant Creutzfeldt-Jakob disease
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    Chapter 43 A pitfall in diagnosis of human prion diseases using detection of protease-resistant prion protein in urine: contamination with bacterial outer membrane proteins
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    Chapter 44 Comparative analysis of chronological data of total tau protein in CSF, serial studies of MRI (DWI, and FLAIR) and staging of clinical features in patients with sporadic CJD
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    Chapter 45 Duration between initial manifestation of CJD and detection of PSD, specific findings on MRI, CSF 14-3-3 protein, or CSF high NSE
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    Chapter 46 Biochemical analysis of peripheral tissue involvement in transmissible spongiform encephalopathies
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    Chapter 47 Involvement of the peripheral nervous system in human prion diseases including dural graft-associated Creutzfeldt-Jakob disease
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    Chapter 48 MM2 type sporadic Creutzfeldt-Jakob disease: clinicoradiologic features and clinical diagnosis
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    Chapter 49 Early clinical and radiological diagnosis of sporadic Creuzfeldt-Jakob’s disease (sCJD) — a case study of pathologically-proved sCJD MV2 —
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    Chapter 50 Familial Creutzfeldt-Jakob disease with a point mutation (Met to Arg) at codon 232: two different phenotypes
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    Chapter 51 Familial Creutzfeldt-Jakob disease with five octapeptide repeat insert
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    Chapter 52 A case of Creutzfeldt-Jakob disease with a novel insertion mutation and codon 219 Lysine/Lysine polymorphism in the prion protein gene
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    Chapter 53 Inhibition of Prion Propagation in Scrapie-infected Cell Lines using Mouse Monoclonal Antibodies against Prion Protein
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    Chapter 54 The inhibitory effect of the ScFv of an anti-prion protein antibody secreted from N2a58 cells on abnormal prion protein accumulation in scrapie-infected cells, ScN2a
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    Chapter 55 Mucosal immunogenicity of prion protein fused with heat-labile enterotoxin B subunit
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    Chapter 56 Identification of drugs that enhance the stimulatory effect of PrP on the fibrinolytic system
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    Chapter 57 Screening study of prion binding agents and their inhibitory effect on the conversion of prion protein
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    Chapter 58 Can Forage Grasses inhibit Prion Replication?
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    Chapter 59 Inhibition of abnormal PrP formation by amyloid-imaging probes in vitro
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    Chapter 60 Treatment with Anti-malaria Agents, Quinacrine and Quinine, for Creutzfeldt - Jakob disease patients
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    Chapter 61 Effect of oral administration of pentosan polysulfate for patients with Creutzfeldt-Jakob disease (CJD) and new design for low molecular-weight of pentosan polysulfate